TY - JOUR
T1 - Interobserver variability of cervical smears with squamous‐cell abnormalities
T2 - A philadelphia study
AU - Young, Nancy A.
AU - Naryshkin, Sonya
AU - Atkinson, Barbara F.
AU - Ehya, Hormoz
AU - Gupta, Prabodh K.
AU - Kline, Tilde S.
AU - Luff, Ronald D.
PY - 1994/12
Y1 - 1994/12
N2 - The reproducibility of reporting squamous lesions by the Bethesda System (TBS) was evaluated by distributing 20 slides to be classified among 5 panelists considered experts in the field of cytopathology. Four cases were chosen for their classic morphology and the remainder were foreseen to produce possible discrepancies within one diagnostic category. For 7/20 (35%) cases there was unanimous agreement. Participants disagreed within one category of magnitude for seven (35%) cases. In six (30%) cases there was a range of more than one category disagreement. However, additional written comments modifying TBS diagnoses often diminished the clinical significance of these discrepancies. We conclude that despite the important role of TBS in standardization of Pap smear reports, a great degree of subjectivity exists in classifying squamous abnormalities without “classic” morphology. The lack of reproducibility should be taken into account in cytology proficiency testing. Diagn Cytopathol 1994;11:352–357. © 1994 Wiley‐Liss, Inc.
AB - The reproducibility of reporting squamous lesions by the Bethesda System (TBS) was evaluated by distributing 20 slides to be classified among 5 panelists considered experts in the field of cytopathology. Four cases were chosen for their classic morphology and the remainder were foreseen to produce possible discrepancies within one diagnostic category. For 7/20 (35%) cases there was unanimous agreement. Participants disagreed within one category of magnitude for seven (35%) cases. In six (30%) cases there was a range of more than one category disagreement. However, additional written comments modifying TBS diagnoses often diminished the clinical significance of these discrepancies. We conclude that despite the important role of TBS in standardization of Pap smear reports, a great degree of subjectivity exists in classifying squamous abnormalities without “classic” morphology. The lack of reproducibility should be taken into account in cytology proficiency testing. Diagn Cytopathol 1994;11:352–357. © 1994 Wiley‐Liss, Inc.
KW - Carcinoma, Squamous Cell/pathology
KW - Cervix Uteri/pathology
KW - Epithelium/pathology
KW - Female
KW - Humans
KW - Observer Variation
KW - Papanicolaou Test
KW - Reproducibility of Results
KW - Uterine Cervical Dysplasia/pathology
KW - Uterine Cervical Neoplasms/pathology
KW - Vaginal Smears/statistics & numerical data
UR - http://www.scopus.com/inward/record.url?scp=0028618612&partnerID=8YFLogxK
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=purepublist2023&SrcAuth=WosAPI&KeyUT=WOS:A1994QF98700007&DestLinkType=FullRecord&DestApp=WOS
U2 - 10.1002/dc.2840110408
DO - 10.1002/dc.2840110408
M3 - Article
C2 - 7895574
SN - 8755-1039
VL - 11
SP - 352
EP - 357
JO - Diagnostic Cytopathology
JF - Diagnostic Cytopathology
IS - 4
ER -