Inclusion complexes in drug delivery and drug targeting: Formation, characterization, and biological applications

Rajesh K.K. Sanku, Ozlem O. Karakus, Monica Ilies, Marc A. Ilies

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

4 Scopus citations

Abstract

Host-guest complexation based on non-covalent interactions can be successfully exploited for drug and nucleic acid delivery purposes. The chapter covers the main classes of hosts used for these applications, namely cyclodextrins, calixarenes, and cucurbiturils and reveals the main representatives and their physicochemical characteristics that modulate the complexation process. It also highlights relevant drugs and nucleic acid complexes, together with the dysfunctions and diseases where the host-guest complexes have been successfully used.

Original languageEnglish
Title of host publicationTargeted Nanosystems for Therapeutic Applications
Subtitle of host publicationNew Concepts, Dynamic Properties, Efficiency, and Toxicity
EditorsKazuo Sakurai, Marc A. Ilies
PublisherAmerican Chemical Society
Pages188-221
Number of pages34
ISBN (Electronic)9780841233836
StatePublished - 2019
Externally publishedYes

Publication series

NameACS Symposium Series
Volume1309
ISSN (Print)0097-6156
ISSN (Electronic)1947-5918

Fingerprint

Dive into the research topics of 'Inclusion complexes in drug delivery and drug targeting: Formation, characterization, and biological applications'. Together they form a unique fingerprint.

Cite this