Immunostimulatory effects of radioimmunotherapy

Julie Constanzo, Lorenzo Galluzzi, Jean Pierre Pouget

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Radiation therapy (RT) is known for its ability to kill cancer cells in an immunogenic manner. Recent preclinical data demonstrate that targeted alpha-particle therapy shares with RT the capacity to elicit immunostimulatory effects, standing out as a promising strategy to circumvent immune checkpoint inhibitor resistance in immunologically € cold' tumors.

Original languageEnglish
Article numbere004403
JournalJournal for ImmunoTherapy of Cancer
Volume10
Issue number2
DOIs
StatePublished - Feb 21 2022
Externally publishedYes

Keywords

  • adaptive immunity
  • immunotherapy
  • interferon inducers
  • radioimmunotherapy
  • Adaptive Immunity/immunology
  • Immune Checkpoint Inhibitors/pharmacology
  • Humans
  • Radioimmunotherapy/methods
  • Immunization/methods

Fingerprint

Dive into the research topics of 'Immunostimulatory effects of radioimmunotherapy'. Together they form a unique fingerprint.

Cite this