Abstract
Radiation therapy (RT) is known for its ability to kill cancer cells in an immunogenic manner. Recent preclinical data demonstrate that targeted alpha-particle therapy shares with RT the capacity to elicit immunostimulatory effects, standing out as a promising strategy to circumvent immune checkpoint inhibitor resistance in immunologically € cold' tumors.
Original language | English |
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Article number | e004403 |
Journal | Journal for ImmunoTherapy of Cancer |
Volume | 10 |
Issue number | 2 |
DOIs | |
State | Published - Feb 21 2022 |
Externally published | Yes |
Keywords
- adaptive immunity
- immunotherapy
- interferon inducers
- radioimmunotherapy
- Adaptive Immunity/immunology
- Immune Checkpoint Inhibitors/pharmacology
- Humans
- Radioimmunotherapy/methods
- Immunization/methods