High-risk medication use for Clostridium difficile infection among hospitalized patients with cancer

A. L. Pakyz; R. Kohinke; P. Opper; S. F. Hohmann; R. M. Jones; P. Nadpara

doi:10.1016/j.ajic.2018.07.016

High-risk medication use for Clostridium difficile infection among hospitalized patients with cancer

A. L. Pakyz, R. Kohinke, P. Opper, S. F. Hohmann, R. M. Jones, P. Nadpara

Cancer Prevention and Control (CPC)

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Patients with cancer are vulnerable to Clostridium difficile infection (CDI); hospitals with larger oncology populations may have worse CDI performance. Among 71 academic hospitals studied, there were significant differences in oncology patient-days per 1,000 admissions across CDI standardized infection ratio categories of better, no different, and worse; worse hospitals had the greatest number of patient-days. Oncology patients' most commonly used high-risk CDI medications were quinolones, third- and fourth-generation cephalosporins, and proton pump inhibitors.

Original language	English
Pages (from-to)	217-219
Number of pages	3
Journal	American Journal of Infection Control
Volume	47
Issue number	2
DOIs	https://doi.org/10.1016/j.ajic.2018.07.016
State	Published - Feb 2019

Keywords

Bone marrow transplant
Chemotherapeutic agents
Clostridium difficile
Oncology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.ajic.2018.07.016

https://www.ncbi.nlm.nih.gov/pubmed/30220616

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title = "High-risk medication use for Clostridium difficile infection among hospitalized patients with cancer",

abstract = "Patients with cancer are vulnerable to Clostridium difficile infection (CDI); hospitals with larger oncology populations may have worse CDI performance. Among 71 academic hospitals studied, there were significant differences in oncology patient-days per 1,000 admissions across CDI standardized infection ratio categories of better, no different, and worse; worse hospitals had the greatest number of patient-days. Oncology patients' most commonly used high-risk CDI medications were quinolones, third- and fourth-generation cephalosporins, and proton pump inhibitors.",

keywords = "Bone marrow transplant, Chemotherapeutic agents, Clostridium difficile, Oncology",

author = "Pakyz, {A. L.} and R. Kohinke and P. Opper and Hohmann, {S. F.} and Jones, {R. M.} and P. Nadpara",

note = "Publisher Copyright: {\textcopyright} 2018 Association for Professionals in Infection Control and Epidemiology, Inc.",

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language = "English",

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AU - Pakyz, A. L.

AU - Kohinke, R.

AU - Opper, P.

AU - Hohmann, S. F.

AU - Jones, R. M.

AU - Nadpara, P.

PY - 2019/2

Y1 - 2019/2

N2 - Patients with cancer are vulnerable to Clostridium difficile infection (CDI); hospitals with larger oncology populations may have worse CDI performance. Among 71 academic hospitals studied, there were significant differences in oncology patient-days per 1,000 admissions across CDI standardized infection ratio categories of better, no different, and worse; worse hospitals had the greatest number of patient-days. Oncology patients' most commonly used high-risk CDI medications were quinolones, third- and fourth-generation cephalosporins, and proton pump inhibitors.

AB - Patients with cancer are vulnerable to Clostridium difficile infection (CDI); hospitals with larger oncology populations may have worse CDI performance. Among 71 academic hospitals studied, there were significant differences in oncology patient-days per 1,000 admissions across CDI standardized infection ratio categories of better, no different, and worse; worse hospitals had the greatest number of patient-days. Oncology patients' most commonly used high-risk CDI medications were quinolones, third- and fourth-generation cephalosporins, and proton pump inhibitors.

KW - Bone marrow transplant

KW - Chemotherapeutic agents

KW - Clostridium difficile

KW - Oncology

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DO - 10.1016/j.ajic.2018.07.016

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JO - American Journal of Infection Control

JF - American Journal of Infection Control

IS - 2

ER -

High-risk medication use for Clostridium difficile infection among hospitalized patients with cancer

Abstract

Keywords

UN SDGs

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