Heavy Metal to Rock the Immune Infiltrate

Lorenzo Galluzzi, Takahiro Yamazaki, Sandra Demaria

Research output: Contribution to journalShort surveypeer-review

9 Scopus citations

Abstract

Two resource articles recently published in Cell demonstrate that the elevated phenotypic complexity of the immune infiltrate in human lung adenocarcinomas and renal cell carcinomas can be reliably dissected with mass cytometry. These findings may pave the way to a new era of precision cancer immunotherapy.

Original languageEnglish
Pages (from-to)539-541
Number of pages3
JournalTrends in Immunology
Volume38
Issue number8
DOIs
StatePublished - Aug 2017
Externally publishedYes

Keywords

  • CD4CD25FOXP3 regulatory T cells
  • CD8 cytotoxic T lymphocytes
  • dendritic cells
  • immune checkpoint blockers
  • natural killer cells
  • tumor-associated macrophages

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