Global loss of promoter–enhancer connectivity and rebalancing of gene expression during early colorectal cancer carcinogenesis

Yizhou Zhu, Hayan Lee, Shannon White, Annika K. Weimer, Emma Monte, Aaron Horning, Stephanie A. Nevins, Edward D. Esplin, Kristina Paul, Gat Krieger, Zohar Shipony, Roxanne Chiu, Rozelle Laquindanum, Thomas V. Karathanos, Melissa W.Y. Chua, Meredith Mills, Uri Ladabaum, Teri Longacre, Jeanne Shen, Ariel JaimovichDoron Lipson, Anshul Kundaje, William J. Greenleaf, Christina Curtis, James M. Ford, Michael P. Snyder

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Biochemistry, Genetics and Molecular Biology