Genetic/Familial high-risk assessment: Colorectal, version 2.2019 featured updates to the NCCN guidelines

Samir Gupta; Dawn Provenzale; Xavier Llor; Amy L. Halverson; William Grady; Daniel C. Chung; Sigurdis Haraldsdottir; Arnold J. Markowitz; Thomas P. Slavin; Heather Hampel; Reid M. Ness; Jennifer M. Weiss; Dennis J. Ahnen; Lee May Chen; Gregory Cooper; Dayna S. Early; Francis M. Giardiello; Michael J. Hall; Stanley R. Hamilton; Priyanka Kanth; Jason B. Klapman; Audrey J. Lazenby; Patrick M. Lynch; Robert J. Mayer; June Mikkelson; Shajan Peter; Scott E. Regenbogen; Mary A. Dwyer; Ndiya Ogba

doi:10.6004/jnccn.2019.0044

Genetic/Familial high-risk assessment: Colorectal, version 2.2019 featured updates to the NCCN guidelines

Samir Gupta, Dawn Provenzale, Xavier Llor, Amy L. Halverson, William Grady, Daniel C. Chung, Sigurdis Haraldsdottir, Arnold J. Markowitz, Thomas P. Slavin, Heather Hampel, Reid M. Ness, Jennifer M. Weiss, Dennis J. Ahnen, Lee May Chen, Gregory Cooper, Dayna S. Early, Francis M. Giardiello, Michael J. Hall, Stanley R. Hamilton, Priyanka KanthJason B. Klapman, Audrey J. Lazenby, Patrick M. Lynch, Robert J. Mayer, June Mikkelson, Shajan Peter, Scott E. Regenbogen, Mary A. Dwyer, Ndiya Ogba

Research output: Contribution to journal › Article › peer-review

191 Scopus citations

Abstract

Identifying individuals with hereditary syndromes allows for improved cancer surveillance, risk reduction, and optimized management. Establishing criteria for assessment allows for the identification of individuals who are carriers of pathogenic genetic variants. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations for the assessment and management of patients with high-risk colorectal cancer syndromes. These NCCN Guidelines Insights focus on criteria for the evaluation of Lynch syndrome and considerations for use of multigene testing in the assessment of hereditary colorectal cancer syndromes.

Original language	English
Pages (from-to)	1032-1041
Number of pages	10
Journal	Journal of the National Comprehensive Cancer Network : JNCCN
Volume	17
Issue number	9
DOIs	https://doi.org/10.6004/jnccn.2019.0044
State	Published - 2019

Keywords

Adenomatous Polyposis Coli/diagnosis
Colorectal Neoplasms/diagnosis
Diagnosis, Differential
Genetic Association Studies
Genetic Predisposition to Disease
Humans
Neoplastic Syndromes, Hereditary/diagnosis
Risk Assessment

Access to Document

10.6004/jnccn.2019.0044

Cite this

Gupta, S., Provenzale, D., Llor, X., Halverson, A. L., Grady, W., Chung, D. C., Haraldsdottir, S., Markowitz, A. J., Slavin, T. P., Hampel, H., Ness, R. M., Weiss, J. M., Ahnen, D. J., Chen, L. M., Cooper, G., Early, D. S., Giardiello, F. M., Hall, M. J., Hamilton, S. R., ... Ogba, N. (2019). Genetic/Familial high-risk assessment: Colorectal, version 2.2019 featured updates to the NCCN guidelines. Journal of the National Comprehensive Cancer Network : JNCCN, 17(9), 1032-1041. https://doi.org/10.6004/jnccn.2019.0044

@article{ddaa1b338a2840618c25bcac6feaa249,

title = "Genetic/Familial high-risk assessment: Colorectal, version 2.2019 featured updates to the NCCN guidelines",

abstract = "Identifying individuals with hereditary syndromes allows for improved cancer surveillance, risk reduction, and optimized management. Establishing criteria for assessment allows for the identification of individuals who are carriers of pathogenic genetic variants. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations for the assessment and management of patients with high-risk colorectal cancer syndromes. These NCCN Guidelines Insights focus on criteria for the evaluation of Lynch syndrome and considerations for use of multigene testing in the assessment of hereditary colorectal cancer syndromes.",

keywords = "Adenomatous Polyposis Coli/diagnosis, Colorectal Neoplasms/diagnosis, Diagnosis, Differential, Genetic Association Studies, Genetic Predisposition to Disease, Humans, Neoplastic Syndromes, Hereditary/diagnosis, Risk Assessment",

author = "Samir Gupta and Dawn Provenzale and Xavier Llor and Halverson, {Amy L.} and William Grady and Chung, {Daniel C.} and Sigurdis Haraldsdottir and Markowitz, {Arnold J.} and Slavin, {Thomas P.} and Heather Hampel and Ness, {Reid M.} and Weiss, {Jennifer M.} and Ahnen, {Dennis J.} and Chen, {Lee May} and Gregory Cooper and Early, {Dayna S.} and Giardiello, {Francis M.} and Hall, {Michael J.} and Hamilton, {Stanley R.} and Priyanka Kanth and Klapman, {Jason B.} and Lazenby, {Audrey J.} and Lynch, {Patrick M.} and Mayer, {Robert J.} and June Mikkelson and Shajan Peter and Regenbogen, {Scott E.} and Dwyer, {Mary A.} and Ndiya Ogba",

year = "2019",

doi = "10.6004/jnccn.2019.0044",

language = "English",

volume = "17",

pages = "1032--1041",

journal = "Journal of the National Comprehensive Cancer Network : JNCCN",

issn = "1540-1405",

publisher = "Cold Spring Publishing LLC",

number = "9",

}

Gupta, S, Provenzale, D, Llor, X, Halverson, AL, Grady, W, Chung, DC, Haraldsdottir, S, Markowitz, AJ, Slavin, TP, Hampel, H, Ness, RM, Weiss, JM, Ahnen, DJ, Chen, LM, Cooper, G, Early, DS, Giardiello, FM, Hall, MJ, Hamilton, SR, Kanth, P, Klapman, JB, Lazenby, AJ, Lynch, PM, Mayer, RJ, Mikkelson, J, Peter, S, Regenbogen, SE, Dwyer, MA & Ogba, N 2019, 'Genetic/Familial high-risk assessment: Colorectal, version 2.2019 featured updates to the NCCN guidelines', Journal of the National Comprehensive Cancer Network : JNCCN, vol. 17, no. 9, pp. 1032-1041. https://doi.org/10.6004/jnccn.2019.0044

TY - JOUR

T1 - Genetic/Familial high-risk assessment

T2 - Colorectal, version 2.2019 featured updates to the NCCN guidelines

AU - Gupta, Samir

AU - Provenzale, Dawn

AU - Llor, Xavier

AU - Halverson, Amy L.

AU - Grady, William

AU - Chung, Daniel C.

AU - Haraldsdottir, Sigurdis

AU - Markowitz, Arnold J.

AU - Slavin, Thomas P.

AU - Hampel, Heather

AU - Ness, Reid M.

AU - Weiss, Jennifer M.

AU - Ahnen, Dennis J.

AU - Chen, Lee May

AU - Cooper, Gregory

AU - Early, Dayna S.

AU - Giardiello, Francis M.

AU - Hall, Michael J.

AU - Hamilton, Stanley R.

AU - Kanth, Priyanka

AU - Klapman, Jason B.

AU - Lazenby, Audrey J.

AU - Lynch, Patrick M.

AU - Mayer, Robert J.

AU - Mikkelson, June

AU - Peter, Shajan

AU - Regenbogen, Scott E.

AU - Dwyer, Mary A.

AU - Ogba, Ndiya

PY - 2019

Y1 - 2019

N2 - Identifying individuals with hereditary syndromes allows for improved cancer surveillance, risk reduction, and optimized management. Establishing criteria for assessment allows for the identification of individuals who are carriers of pathogenic genetic variants. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations for the assessment and management of patients with high-risk colorectal cancer syndromes. These NCCN Guidelines Insights focus on criteria for the evaluation of Lynch syndrome and considerations for use of multigene testing in the assessment of hereditary colorectal cancer syndromes.

AB - Identifying individuals with hereditary syndromes allows for improved cancer surveillance, risk reduction, and optimized management. Establishing criteria for assessment allows for the identification of individuals who are carriers of pathogenic genetic variants. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations for the assessment and management of patients with high-risk colorectal cancer syndromes. These NCCN Guidelines Insights focus on criteria for the evaluation of Lynch syndrome and considerations for use of multigene testing in the assessment of hereditary colorectal cancer syndromes.

KW - Adenomatous Polyposis Coli/diagnosis

KW - Colorectal Neoplasms/diagnosis

KW - Diagnosis, Differential

KW - Genetic Association Studies

KW - Genetic Predisposition to Disease

KW - Humans

KW - Neoplastic Syndromes, Hereditary/diagnosis

KW - Risk Assessment

UR - http://www.scopus.com/inward/record.url?scp=85071737330&partnerID=8YFLogxK

UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=purepublist2023&SrcAuth=WosAPI&KeyUT=WOS:000487242700003&DestLinkType=FullRecord&DestApp=WOS

U2 - 10.6004/jnccn.2019.0044

DO - 10.6004/jnccn.2019.0044

M3 - Article

C2 - 31487681

SN - 1540-1405

VL - 17

SP - 1032

EP - 1041

JO - Journal of the National Comprehensive Cancer Network : JNCCN

JF - Journal of the National Comprehensive Cancer Network : JNCCN

IS - 9

ER -

Genetic/Familial high-risk assessment: Colorectal, version 2.2019 featured updates to the NCCN guidelines

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this