Genetic/familial high-risk assessment: Breast and ovarian. Clinical Practice Guidelines in Oncology™

Mary B. Daly; Jennifer E. Axilbund; Eileen Bryant; Saundra Buys; Charis Eng; Susan Friedman; Laura J. Esserman; Carolyn D. Farrell; James M. Ford; Judy E. Garber; Joanne M. Jeter; Wendy Kohlmann; Patrick M. Lynch; P. Kelly Marcom; Lisle M. Nabell; Kenneth Offit; Raymond U. Osarogiagbon; Boris Pasche; Gwen Reiser; Rebecca Sutphen; Jeffrey N. Weitzel

doi:10.6004/jnccn.2006.0016

Genetic/familial high-risk assessment: Breast and ovarian. Clinical Practice Guidelines in Oncology™

Mary B. Daly
, Jennifer E. Axilbund
, Eileen Bryant
, Saundra Buys
, Charis Eng
, Susan Friedman
, Laura J. Esserman
, Carolyn D. Farrell
, James M. Ford
, Judy E. Garber
, Joanne M. Jeter
, Wendy Kohlmann
, Patrick M. Lynch
, P. Kelly Marcom
, Lisle M. Nabell
, Kenneth Offit
, Raymond U. Osarogiagbon
, Boris Pasche
, Gwen Reiser
, Rebecca Sutphen

Jeffrey N. Weitzel

Johns Hopkins University
Seattle Cancer Care Alliance
University of Utah
Cleveland Clinic Foundation
FORCE: Facing Our Risk of Cancer Empowered
University of California at San Francisco
Roswell Park Cancer Institute
Stanford University
Dana-Farber/Partners CancerCare
University of Michigan, Ann Arbor
University of Texas MD Anderson Cancer Center
Duke University
University of Alabama at Birmingham
Memorial Sloan-Kettering Cancer Center
University of Tennessee System
Northwestern University
Nebraska Medicine
University of South Florida
City of Hope National Medical Center

Research output: Contribution to journal › Review article › peer-review

47 Scopus citations

Abstract

Recent advances in molecular genetics have identified several genes associated with inherited susceptibility to cancer and have provided a means to begin identifying individuals and families with an increased risk of cancer. This rapid expansion of knowledge about cancer genetics has implications for all aspects of cancer management, including prevention, screening, and treatment. These guidelines specifically address hereditary breast/ovarian cancer syndrome (HBOC), Li-Fraumeni syndrome, and Cowden syndrome. These guidelines were developed understanding that much of our knowledge of how the rapidly emerging field of molecular genetics can be applied clinically is preliminary and that flexibility is needed when applying these guidelines to individual families.

Original language	English
Pages (from-to)	156-176
Number of pages	21
Journal	Journal of the National Comprehensive Cancer Network : JNCCN
Volume	4
Issue number	2
DOIs	https://doi.org/10.6004/jnccn.2006.0016
State	Published - Feb 2006

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

BRCA1
BRCA2
Breast/ovarian cancer syndrome
Cowden syndrome
Gene
Genetic counseling
Genetic risk assessment
Hereditary
Li-Fraumeni syndrome
NCCN Clinical Practice Guidelines

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10.6004/jnccn.2006.0016

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Daly, M. B., Axilbund, J. E., Bryant, E., Buys, S., Eng, C., Friedman, S., Esserman, L. J., Farrell, C. D., Ford, J. M., Garber, J. E., Jeter, J. M., Kohlmann, W., Lynch, P. M., Marcom, P. K., Nabell, L. M., Offit, K., Osarogiagbon, R. U., Pasche, B., Reiser, G., ... Weitzel, J. N. (2006). Genetic/familial high-risk assessment: Breast and ovarian. Clinical Practice Guidelines in Oncology™. Journal of the National Comprehensive Cancer Network : JNCCN, 4(2), 156-176. https://doi.org/10.6004/jnccn.2006.0016

@article{8bb26d005eef4217bec2555a6143b800,

title = "Genetic/familial high-risk assessment: Breast and ovarian. Clinical Practice Guidelines in Oncology{\texttrademark}",

abstract = "Recent advances in molecular genetics have identified several genes associated with inherited susceptibility to cancer and have provided a means to begin identifying individuals and families with an increased risk of cancer. This rapid expansion of knowledge about cancer genetics has implications for all aspects of cancer management, including prevention, screening, and treatment. These guidelines specifically address hereditary breast/ovarian cancer syndrome (HBOC), Li-Fraumeni syndrome, and Cowden syndrome. These guidelines were developed understanding that much of our knowledge of how the rapidly emerging field of molecular genetics can be applied clinically is preliminary and that flexibility is needed when applying these guidelines to individual families.",

keywords = "BRCA1, BRCA2, Breast/ovarian cancer syndrome, Cowden syndrome, Gene, Genetic counseling, Genetic risk assessment, Hereditary, Li-Fraumeni syndrome, NCCN Clinical Practice Guidelines",

author = "Daly, \{Mary B.\} and Axilbund, \{Jennifer E.\} and Eileen Bryant and Saundra Buys and Charis Eng and Susan Friedman and Esserman, \{Laura J.\} and Farrell, \{Carolyn D.\} and Ford, \{James M.\} and Garber, \{Judy E.\} and Jeter, \{Joanne M.\} and Wendy Kohlmann and Lynch, \{Patrick M.\} and Marcom, \{P. Kelly\} and Nabell, \{Lisle M.\} and Kenneth Offit and Osarogiagbon, \{Raymond U.\} and Boris Pasche and Gwen Reiser and Rebecca Sutphen and Weitzel, \{Jeffrey N.\}",

year = "2006",

month = feb,

doi = "10.6004/jnccn.2006.0016",

language = "English",

volume = "4",

pages = "156--176",

journal = "Journal of the National Comprehensive Cancer Network : JNCCN",

issn = "1540-1405",

publisher = "Harborside Press",

number = "2",

}

Daly, MB, Axilbund, JE, Bryant, E, Buys, S, Eng, C, Friedman, S, Esserman, LJ, Farrell, CD, Ford, JM, Garber, JE, Jeter, JM, Kohlmann, W, Lynch, PM, Marcom, PK, Nabell, LM, Offit, K, Osarogiagbon, RU, Pasche, B, Reiser, G, Sutphen, R & Weitzel, JN 2006, 'Genetic/familial high-risk assessment: Breast and ovarian. Clinical Practice Guidelines in Oncology™', Journal of the National Comprehensive Cancer Network : JNCCN, vol. 4, no. 2, pp. 156-176. https://doi.org/10.6004/jnccn.2006.0016

TY - JOUR

T1 - Genetic/familial high-risk assessment

T2 - Breast and ovarian. Clinical Practice Guidelines in Oncology™

AU - Daly, Mary B.

AU - Axilbund, Jennifer E.

AU - Bryant, Eileen

AU - Buys, Saundra

AU - Eng, Charis

AU - Friedman, Susan

AU - Esserman, Laura J.

AU - Farrell, Carolyn D.

AU - Ford, James M.

AU - Garber, Judy E.

AU - Jeter, Joanne M.

AU - Kohlmann, Wendy

AU - Lynch, Patrick M.

AU - Marcom, P. Kelly

AU - Nabell, Lisle M.

AU - Offit, Kenneth

AU - Osarogiagbon, Raymond U.

AU - Pasche, Boris

AU - Reiser, Gwen

AU - Sutphen, Rebecca

AU - Weitzel, Jeffrey N.

PY - 2006/2

Y1 - 2006/2

N2 - Recent advances in molecular genetics have identified several genes associated with inherited susceptibility to cancer and have provided a means to begin identifying individuals and families with an increased risk of cancer. This rapid expansion of knowledge about cancer genetics has implications for all aspects of cancer management, including prevention, screening, and treatment. These guidelines specifically address hereditary breast/ovarian cancer syndrome (HBOC), Li-Fraumeni syndrome, and Cowden syndrome. These guidelines were developed understanding that much of our knowledge of how the rapidly emerging field of molecular genetics can be applied clinically is preliminary and that flexibility is needed when applying these guidelines to individual families.

AB - Recent advances in molecular genetics have identified several genes associated with inherited susceptibility to cancer and have provided a means to begin identifying individuals and families with an increased risk of cancer. This rapid expansion of knowledge about cancer genetics has implications for all aspects of cancer management, including prevention, screening, and treatment. These guidelines specifically address hereditary breast/ovarian cancer syndrome (HBOC), Li-Fraumeni syndrome, and Cowden syndrome. These guidelines were developed understanding that much of our knowledge of how the rapidly emerging field of molecular genetics can be applied clinically is preliminary and that flexibility is needed when applying these guidelines to individual families.

KW - BRCA1

KW - BRCA2

KW - Breast/ovarian cancer syndrome

KW - Cowden syndrome

KW - Gene

KW - Genetic counseling

KW - Genetic risk assessment

KW - Hereditary

KW - Li-Fraumeni syndrome

KW - NCCN Clinical Practice Guidelines

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DO - 10.6004/jnccn.2006.0016

M3 - Review article

C2 - 16451772

AN - SCOPUS:33646834238

SN - 1540-1405

VL - 4

SP - 156

EP - 176

JO - Journal of the National Comprehensive Cancer Network : JNCCN

JF - Journal of the National Comprehensive Cancer Network : JNCCN

IS - 2

ER -

Genetic/familial high-risk assessment: Breast and ovarian. Clinical Practice Guidelines in Oncology™

Abstract

UN SDGs

Keywords

Access to Document

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