Extramedullary plasmacytoma confined to the choroid

Santosh G. Honavar; Jerry A. Shields; Carol L. Shields; Hakan Demirci; Hormoz Ehya

doi:10.1016/S0002-9394(00)00706-6

Extramedullary plasmacytoma confined to the choroid

Santosh G. Honavar, Jerry A. Shields, Carol L. Shields, Hakan Demirci, Hormoz Ehya

Pathology

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

PURPOSE: To report a case of an extramedullary plasmacytoma confined to the choroid.METHODS: Interventional case report with cytopathologic correlation. RESULTS: A 76-year-old asymptomatic woman presented with 2 globular orange and amelanotic choroidal lesions in the right eye. Fine needle aspiration biopsy of one of the choroidal lesions followed by immunocytochemical studies revealed monoclonal plasma cells, diagnostic of plasmacytoma. Systemic evaluation was negative, except for increased serum gamma globulin with immunoglobulin kappa spike on electrophoresis. The patient was managed by ocular external beam radiotherapy. At 9 years follow-up, she was free of local disease and never developed multiple myeloma. CONCLUSION: Extramedullary plasmacytoma confined to the choroid is rare. It may present simulating other common amelanotic choroidal lesions. Fine needle aspiration biopsy and proper systemic evaluation are critical in establishing the diagnosis.

Original language	English
Pages (from-to)	277-278
Number of pages	2
Journal	American Journal of Ophthalmology
Volume	131
Issue number	2
DOIs	https://doi.org/10.1016/S0002-9394(00)00706-6
State	Published - 2001

Keywords

Aged
Choroid Neoplasms/diagnostic imaging
Female
Humans
Plasmacytoma/diagnostic imaging
Ultrasonography

Access to Document

10.1016/S0002-9394(00)00706-6

Cite this

@article{ade3e47bf0a44464a174926c6994bb6c,

title = "Extramedullary plasmacytoma confined to the choroid",

abstract = "PURPOSE: To report a case of an extramedullary plasmacytoma confined to the choroid.METHODS: Interventional case report with cytopathologic correlation. RESULTS: A 76-year-old asymptomatic woman presented with 2 globular orange and amelanotic choroidal lesions in the right eye. Fine needle aspiration biopsy of one of the choroidal lesions followed by immunocytochemical studies revealed monoclonal plasma cells, diagnostic of plasmacytoma. Systemic evaluation was negative, except for increased serum gamma globulin with immunoglobulin kappa spike on electrophoresis. The patient was managed by ocular external beam radiotherapy. At 9 years follow-up, she was free of local disease and never developed multiple myeloma. CONCLUSION: Extramedullary plasmacytoma confined to the choroid is rare. It may present simulating other common amelanotic choroidal lesions. Fine needle aspiration biopsy and proper systemic evaluation are critical in establishing the diagnosis.",

keywords = "Aged, Choroid Neoplasms/diagnostic imaging, Female, Humans, Plasmacytoma/diagnostic imaging, Ultrasonography",

author = "Honavar, {Santosh G.} and Shields, {Jerry A.} and Shields, {Carol L.} and Hakan Demirci and Hormoz Ehya",

year = "2001",

doi = "10.1016/S0002-9394(00)00706-6",

language = "English",

volume = "131",

pages = "277--278",

journal = "American Journal of Ophthalmology",

issn = "0002-9394",

publisher = "Elsevier USA",

number = "2",

}

TY - JOUR

T1 - Extramedullary plasmacytoma confined to the choroid

AU - Honavar, Santosh G.

AU - Shields, Jerry A.

AU - Shields, Carol L.

AU - Demirci, Hakan

AU - Ehya, Hormoz

PY - 2001

Y1 - 2001

N2 - PURPOSE: To report a case of an extramedullary plasmacytoma confined to the choroid.METHODS: Interventional case report with cytopathologic correlation. RESULTS: A 76-year-old asymptomatic woman presented with 2 globular orange and amelanotic choroidal lesions in the right eye. Fine needle aspiration biopsy of one of the choroidal lesions followed by immunocytochemical studies revealed monoclonal plasma cells, diagnostic of plasmacytoma. Systemic evaluation was negative, except for increased serum gamma globulin with immunoglobulin kappa spike on electrophoresis. The patient was managed by ocular external beam radiotherapy. At 9 years follow-up, she was free of local disease and never developed multiple myeloma. CONCLUSION: Extramedullary plasmacytoma confined to the choroid is rare. It may present simulating other common amelanotic choroidal lesions. Fine needle aspiration biopsy and proper systemic evaluation are critical in establishing the diagnosis.

AB - PURPOSE: To report a case of an extramedullary plasmacytoma confined to the choroid.METHODS: Interventional case report with cytopathologic correlation. RESULTS: A 76-year-old asymptomatic woman presented with 2 globular orange and amelanotic choroidal lesions in the right eye. Fine needle aspiration biopsy of one of the choroidal lesions followed by immunocytochemical studies revealed monoclonal plasma cells, diagnostic of plasmacytoma. Systemic evaluation was negative, except for increased serum gamma globulin with immunoglobulin kappa spike on electrophoresis. The patient was managed by ocular external beam radiotherapy. At 9 years follow-up, she was free of local disease and never developed multiple myeloma. CONCLUSION: Extramedullary plasmacytoma confined to the choroid is rare. It may present simulating other common amelanotic choroidal lesions. Fine needle aspiration biopsy and proper systemic evaluation are critical in establishing the diagnosis.

KW - Aged

KW - Choroid Neoplasms/diagnostic imaging

KW - Female

KW - Humans

KW - Plasmacytoma/diagnostic imaging

KW - Ultrasonography

UR - http://www.scopus.com/inward/record.url?scp=0035134344&partnerID=8YFLogxK

U2 - 10.1016/S0002-9394(00)00706-6

DO - 10.1016/S0002-9394(00)00706-6

M3 - Article

C2 - 11228316

SN - 0002-9394

VL - 131

SP - 277

EP - 278

JO - American Journal of Ophthalmology

JF - American Journal of Ophthalmology

IS - 2

ER -

Extramedullary plasmacytoma confined to the choroid

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this