Epithelioid sarcoma. Ultrastructural similarity to nodular synovitis

Arthur S. Patchefsky; Raymond Soriano; Mery Kostianovsky

doi:10.1002/1097-0142(197701)39:1<143::AID-CNCR2820390125>3.0.CO;2-3

Epithelioid sarcoma. Ultrastructural similarity to nodular synovitis

Arthur S. Patchefsky, Raymond Soriano, Mery Kostianovsky

Pathology

Thomas Jefferson University

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Abstract

The ultrastructure of nodular synovitis of the knee and epithelioid sarcoma of the hand are compared. Both lesions show a similar pattern of light and dark cells having filopodia and microvilli, an outer coat of finely granular matrix without well defined basal laminae, maculae adherentes and attachment sites, pinocytotic vesicles, cytoplasmic filaments and complex nuclear invaginations. These similarities suggest a common histogenesis and support the concept that the epithelioid sarcoma is derived from synovioblastic mesenchyme.

Original language	English
Pages (from-to)	143-152
Number of pages	10
Journal	Cancer
Volume	39
Issue number	1
DOIs	https://doi.org/10.1002/1097-0142(197701)39:1<143::AID-CNCR2820390125>3.0.CO;2-3
State	Published - Jan 1977

Keywords

Cell Membrane/ultrastructure
Cell Nucleus/ultrastructure
Cytoskeleton/ultrastructure
Female
Hand
Humans
Knee
Middle Aged
Sarcoma, Synovial/etiology
Sarcoma/etiology
Soft Tissue Neoplasms/etiology
Synovial Membrane/ultrastructure
Synovitis/pathology

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10.1002/1097-0142(197701)39:1<143::AID-CNCR2820390125>3.0.CO;2-3

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title = "Epithelioid sarcoma. Ultrastructural similarity to nodular synovitis",

abstract = "The ultrastructure of nodular synovitis of the knee and epithelioid sarcoma of the hand are compared. Both lesions show a similar pattern of light and dark cells having filopodia and microvilli, an outer coat of finely granular matrix without well defined basal laminae, maculae adherentes and attachment sites, pinocytotic vesicles, cytoplasmic filaments and complex nuclear invaginations. These similarities suggest a common histogenesis and support the concept that the epithelioid sarcoma is derived from synovioblastic mesenchyme.",

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N2 - The ultrastructure of nodular synovitis of the knee and epithelioid sarcoma of the hand are compared. Both lesions show a similar pattern of light and dark cells having filopodia and microvilli, an outer coat of finely granular matrix without well defined basal laminae, maculae adherentes and attachment sites, pinocytotic vesicles, cytoplasmic filaments and complex nuclear invaginations. These similarities suggest a common histogenesis and support the concept that the epithelioid sarcoma is derived from synovioblastic mesenchyme.

AB - The ultrastructure of nodular synovitis of the knee and epithelioid sarcoma of the hand are compared. Both lesions show a similar pattern of light and dark cells having filopodia and microvilli, an outer coat of finely granular matrix without well defined basal laminae, maculae adherentes and attachment sites, pinocytotic vesicles, cytoplasmic filaments and complex nuclear invaginations. These similarities suggest a common histogenesis and support the concept that the epithelioid sarcoma is derived from synovioblastic mesenchyme.

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KW - Cytoskeleton/ultrastructure

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KW - Hand

KW - Humans

KW - Knee

KW - Middle Aged

KW - Sarcoma, Synovial/etiology

KW - Sarcoma/etiology

KW - Soft Tissue Neoplasms/etiology

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KW - Synovitis/pathology

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Epithelioid sarcoma. Ultrastructural similarity to nodular synovitis

Abstract

Keywords

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