Endourological management of a rare radiopaque ritonavir-composed urinary calculus

Folawiyo Laditi; Amir Ishaq Khan; Eric M. Ghiraldi; Tashzna Jones; Ankur Choksi; Dinesh Singh

doi:10.1016/j.eucr.2021.101763

Endourological management of a rare radiopaque ritonavir-composed urinary calculus

Folawiyo Laditi, Amir Ishaq Khan, Eric M. Ghiraldi, Tashzna Jones, Ankur Choksi, Dinesh Singh

Yale University

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Protease inhibitors are a source of nephrolithiasis in HIV + patients, and these stones are described as not detected by CT. While urinary stones are commonly associated with certain protease inhibitors, stones composed of ritonavir are rare. We present the case of a 58-year-old female on ritonavir-boosted atazanavir who presented to our clinic complaining of gross hematuria and flank pain secondary to a ureteral stone. Surgical removal revealed the stone to be composed of 100% ritonavir with no usual urinary stone components. This is the first report of an HIV medicine stone being detectable by CT scan described as 100% ritonavir.

Original language	English
Article number	101763
Pages (from-to)	101763
Journal	Urology Case Reports
Volume	39
DOIs	https://doi.org/10.1016/j.eucr.2021.101763
State	Published - Nov 2021

Keywords

CT
Endourology
HIV/AIDS
Kidney stone
Ritonavir
Urolithiasis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.eucr.2021.101763

Cite this

@article{a64743a4a1ab47b2a3303c97aef538c2,

title = "Endourological management of a rare radiopaque ritonavir-composed urinary calculus",

abstract = "Protease inhibitors are a source of nephrolithiasis in HIV + patients, and these stones are described as not detected by CT. While urinary stones are commonly associated with certain protease inhibitors, stones composed of ritonavir are rare. We present the case of a 58-year-old female on ritonavir-boosted atazanavir who presented to our clinic complaining of gross hematuria and flank pain secondary to a ureteral stone. Surgical removal revealed the stone to be composed of 100% ritonavir with no usual urinary stone components. This is the first report of an HIV medicine stone being detectable by CT scan described as 100% ritonavir.",

keywords = "CT, Endourology, HIV/AIDS, Kidney stone, Ritonavir, Urolithiasis",

author = "Folawiyo Laditi and Khan, {Amir Ishaq} and Ghiraldi, {Eric M.} and Tashzna Jones and Ankur Choksi and Dinesh Singh",

note = "Publisher Copyright: {\textcopyright} 2021",

year = "2021",

month = nov,

doi = "10.1016/j.eucr.2021.101763",

language = "English",

volume = "39",

pages = "101763",

journal = "Urology Case Reports",

issn = "2214-4420",

publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - Endourological management of a rare radiopaque ritonavir-composed urinary calculus

AU - Laditi, Folawiyo

AU - Khan, Amir Ishaq

AU - Ghiraldi, Eric M.

AU - Jones, Tashzna

AU - Choksi, Ankur

AU - Singh, Dinesh

PY - 2021/11

Y1 - 2021/11

N2 - Protease inhibitors are a source of nephrolithiasis in HIV + patients, and these stones are described as not detected by CT. While urinary stones are commonly associated with certain protease inhibitors, stones composed of ritonavir are rare. We present the case of a 58-year-old female on ritonavir-boosted atazanavir who presented to our clinic complaining of gross hematuria and flank pain secondary to a ureteral stone. Surgical removal revealed the stone to be composed of 100% ritonavir with no usual urinary stone components. This is the first report of an HIV medicine stone being detectable by CT scan described as 100% ritonavir.

AB - Protease inhibitors are a source of nephrolithiasis in HIV + patients, and these stones are described as not detected by CT. While urinary stones are commonly associated with certain protease inhibitors, stones composed of ritonavir are rare. We present the case of a 58-year-old female on ritonavir-boosted atazanavir who presented to our clinic complaining of gross hematuria and flank pain secondary to a ureteral stone. Surgical removal revealed the stone to be composed of 100% ritonavir with no usual urinary stone components. This is the first report of an HIV medicine stone being detectable by CT scan described as 100% ritonavir.

KW - CT

KW - Endourology

KW - HIV/AIDS

KW - Kidney stone

KW - Ritonavir

KW - Urolithiasis

UR - http://www.scopus.com/inward/record.url?scp=85109527824&partnerID=8YFLogxK

U2 - 10.1016/j.eucr.2021.101763

DO - 10.1016/j.eucr.2021.101763

M3 - Article

C2 - 34295648

AN - SCOPUS:85109527824

SN - 2214-4420

VL - 39

SP - 101763

JO - Urology Case Reports

JF - Urology Case Reports

M1 - 101763

ER -

Endourological management of a rare radiopaque ritonavir-composed urinary calculus

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this