Efficient and synergetic DNA delivery with pyridinium amphiphiles-gold nanoparticle composite systems having different packing parameters

Adrian Kizewski; Marc A. Ilies

doi:10.1039/c5cc05760d

Efficient and synergetic DNA delivery with pyridinium amphiphiles-gold nanoparticle composite systems having different packing parameters

Adrian Kizewski
, Marc A. Ilies

Cancer Signaling and Microenvironment (CSM)

College of Science and Technology
Temple University

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Mixtures of highly curved pyridinium-decorated Au nanoparticles and standard pyridinium cationic lipids efficiently and synergetically transfected DNA in vitro, while displaying an excellent cytotoxic profile.

Original language	English
Pages (from-to)	60-63
Number of pages	4
Journal	Chemical Communications
Volume	52
Issue number	1
DOIs	https://doi.org/10.1039/c5cc05760d
State	Published - 2016

Keywords

Cell Line, Tumor
DNA/administration & dosage
Gold/chemistry
Humans
Nanoparticles/chemistry
Pyridinium Compounds/chemistry
Surface-Active Agents/chemistry
Transfection

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10.1039/c5cc05760d

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title = "Efficient and synergetic DNA delivery with pyridinium amphiphiles-gold nanoparticle composite systems having different packing parameters",

abstract = "Mixtures of highly curved pyridinium-decorated Au nanoparticles and standard pyridinium cationic lipids efficiently and synergetically transfected DNA in vitro, while displaying an excellent cytotoxic profile.",

keywords = "Cell Line, Tumor, DNA/administration \& dosage, Gold/chemistry, Humans, Nanoparticles/chemistry, Pyridinium Compounds/chemistry, Surface-Active Agents/chemistry, Transfection",

author = "Adrian Kizewski and Ilies, \{Marc A.\}",

note = "Publisher Copyright: {\textcopyright} 2016 The Royal Society of Chemistry.",

year = "2016",

doi = "10.1039/c5cc05760d",

language = "English",

volume = "52",

pages = "60--63",

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T1 - Efficient and synergetic DNA delivery with pyridinium amphiphiles-gold nanoparticle composite systems having different packing parameters

AU - Kizewski, Adrian

AU - Ilies, Marc A.

PY - 2016

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N2 - Mixtures of highly curved pyridinium-decorated Au nanoparticles and standard pyridinium cationic lipids efficiently and synergetically transfected DNA in vitro, while displaying an excellent cytotoxic profile.

AB - Mixtures of highly curved pyridinium-decorated Au nanoparticles and standard pyridinium cationic lipids efficiently and synergetically transfected DNA in vitro, while displaying an excellent cytotoxic profile.

KW - Cell Line, Tumor

KW - DNA/administration & dosage

KW - Gold/chemistry

KW - Humans

KW - Nanoparticles/chemistry

KW - Pyridinium Compounds/chemistry

KW - Surface-Active Agents/chemistry

KW - Transfection

UR - https://www.scopus.com/pages/publications/84950336305

U2 - 10.1039/c5cc05760d

DO - 10.1039/c5cc05760d

M3 - Article

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AN - SCOPUS:84950336305

SN - 1359-7345

VL - 52

SP - 60

EP - 63

JO - Chemical Communications

JF - Chemical Communications

IS - 1

ER -

Efficient and synergetic DNA delivery with pyridinium amphiphiles-gold nanoparticle composite systems having different packing parameters

Abstract

Keywords

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