Drug therapy versus electroconvulsive therapy for refractory schizophrenia: Report of a case with 14 years of follow-up

Wei Min Dang, Tian Hang Zhou, Mo Zhou, Han Zhi Luo, Wen Sheng Huang, Qing Mei Kong, Lian Sheng Gao, Hong Ping Yao, Jin Pang

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The long-term efficacy and safety of electroconvulsive therapy (ECT) for refractory schizophrenia is rarely reported. We report the case of a 38-year-old female patient with refractory schizophrenia who was treated with ECT for 14 years (from 24 years of age). Case records of clinical treatment and laboratory tests are described and analyzed. During the first 11 years, the patient was treated with ECT as an adjunct to antipsychotic drugs, but the effectiveness was unstable. For the remaining 3 years she was treated with antipsychotic drugs as an adjunct to ECT and her condition stabilized as she gradually recovered social function. We summarize the clinical characteristics, therapy regimen, long-term effectiveness, and safety of this interesting case.

Original languageEnglish
Pages (from-to)245-260
Number of pages16
JournalInternational Journal of Psychiatry in Medicine
Volume45
Issue number3
DOIs
StatePublished - Jan 1 2013
Externally publishedYes

Keywords

  • efficacy
  • long-term ECT
  • refractory schizophrenia
  • safety

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