Dominant-negative histone H3 lysine 27 mutant derepresses silenced tumor suppressor genes and reverses the drug-resistant phenotype in cancer cells

Phillip H. Abbosh, John S. Montgomery, Jason A. Starkey, Milos Novotny, Eleanor G. Zuhowski, Merrill J. Egorin, Annie P. Moseman, Adam Golas, Kate M. Brannon, Curtis Balch, Tim H.M. Huang, Kenneth P. Nephew

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Biochemistry, Genetics and Molecular Biology