Abstract
OBJECTIVE: To assess the diagnostic criteria for grade 1 papillary transitional cell carcinoma (TCC) in cystoscopically obtained urine.
STUDY DESIGN: We compared the sensitivity, specificity and positive predictive value of cytologic, architectural and morphometric (primarily architectural) criteria in 177 specimens with corresponding biopsy follow-up.
RESULTS: Sensitivities ranged from 22% to 44%, specificities from 69% to 85% and positive predictive values from 59% to 66%.
CONCLUSION: The currently described cytologic, architectural and morphometric criteria are inadequate for the identification of grade 1 papillary TCC, and the cytologic diagnosis of grade 1 papillary TCC in cystoscopically obtained urine remains unreliable.
Original language | English |
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Pages (from-to) | 676-682 |
Number of pages | 7 |
Journal | Acta Cytologica |
Volume | 40 |
Issue number | 4 |
DOIs | |
State | Published - 1996 |
Keywords
- Biopsy
- Carcinoma, Transitional Cell/pathology
- Coloring Agents
- Diagnosis, Differential
- Female
- Humans
- Predictive Value of Tests
- Sensitivity and Specificity
- Urinary Bladder Neoplasms/pathology
- Urine/cytology