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Cytochemical characterization of mouse l1210 leukemia

  • J. Kawiak
  • , T. Skorski
  • , A. Ciechanowicz
  • , M. Zylińska
  • , H. J. Seidel
  • , M. Kawalec
  • , B. Gnatowski
  • , A. Czarnomska
  • Medical Centre for Postgraduate Education, Warsaw
  • Pomeranian Medical University in Szczecin
  • Ulm University
  • Centralny Szpital Kliniczny Wojskowej Akademii Medycznej z Poliklinika
  • Maria Sklodowska-Curie Institute of Oncology

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Mouse lymphatic leukemia L1210 cells were characterized with polyclonal and monoclonal antibodies and lectins. The cells were found to have the phenotype IgG-, Thy-1.2-, Lyt-1-, Lyt-2-, asialo-GM1-, TL-, I-Ad-, IL-2R+, peanut agglutinin+, and Helix pomatia lectin +/-. They retained expression of H-2Kd and H-2Dd. Thus, these cells resemble "null" cells.

Original languageEnglish
Pages (from-to)543-550
Number of pages8
JournalImmunological Investigations
Volume17
Issue number6-7
DOIs
StatePublished - 1988

Keywords

  • Animals
  • Antibodies, Monoclonal
  • Antigens, Surface/analysis
  • Epitopes/immunology
  • Lectins
  • Leukemia L1210/chemically induced
  • Liver/immunology
  • Mice
  • Mice, Nude
  • Microscopy, Fluorescence
  • Rabbits
  • Spleen/immunology

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