Corrigendum: CD8 T cell response and its released cytokine IFN-γ are necessary for lung alveolar epithelial repair during bacterial pneumonia (Frontiers in Immunology, (2023), 14, (1268078), 10.3389/fimmu.2023.1268078)

Xiaoying Zhang, Mir Ali, Morgan Alexandra Pantuck, Xiaofeng Yang, Chih Ru Lin, Karim Bahmed, Beata Kosmider, Ying Tian

Research output: Contribution to journalArticlepeer-review

Abstract

In the published article, there was an error in Figure 1C as published. In Figure 1, “2 dpi” and “7 dpi” were intended to depict separate cells. However, an overlapping region was mistakenly included. The corrected version of Figure 1 and its caption appear below. Correlation of CD8 T cell accumulation in the lung and AT2 cell proliferation in SpT4-infected mice. Lung tissues were collected at 0, 1, 2, 4, 7 and 14 days post SpT4 infection (dpi). (A) Flow cytometry analysis on dissociated lung cells at 0, 2, 4, 7 and 14 dpi. (B) Quantification of flow cytometry data showing the percentage of CD8+CD3+CD45+ cells of total live CD45+ cells in the lung at indicated time points. (C) Confocal images of lung sections at 0, 2, 4, 7, and 14 dpi. AT2 cells in DNA synthesis-phase were detected using Click-iT EdU Alexa Fluor (red) and co-immunostaining with antibody against Pro-SPC (green) to detect AT2 cells. Cell nuclear was stained with DAPI (blue). Arrows point to regions double positive for EdU and Pro- SPC. Scale bar: 10 μm. (D) Quantification of EdU+Pro-SPC+ cells as percentage of total Pro- SPC+ cells analyzed (≥10 randomly selected fields per mouse). (B, D) 3-8 mice per time point. Data are presented as mean ± s.e.m. P values were calculated using one-way ANOVA. * P < 0.05; **** P < 0.0001. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Original languageEnglish
Article number1446350
Pages (from-to)1446350
JournalFrontiers in Immunology
Volume15
DOIs
StatePublished - 2024

Keywords

  • alveolar epithelial cells
  • repair
  • IFN-γ
  • CD8 T-cell
  • acute lung injury

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