Conformational dynamics of nonsynonymous variants at protein interfaces reveals disease association

BM Butler, ZN Gerek, S Kumar, SB Ozkan

Research output: Contribution to journalArticlepeer-review

30 Scopus citations
Original languageAmerican English
Pages (from-to)428-435
Number of pages8
JournalProteins-structure Function and Bioinformatics
Volume83
Issue number3
DOIs
StatePublished - Mar 2015

Keywords

  • Conformational dynamics
  • Dynamic flexibility
  • Elastic network model
  • Evolutionary conservation
  • Interfaces
  • Linear response theory
  • Perturbation response scanning
  • Phenotypic prediction
  • Protein-protein interactions
  • Single nucleotide polymorphisms

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