Cloning and regional assignment of the human myosin heavy chain 12 (MYH12) gene to chromosome band 15q21

K. J. Moore; J. R. Testa; U. Francke; A. Milatovich; N. G. Copeland; Nancy A. Jenkins

doi:10.1159/000133937

Cloning and regional assignment of the human myosin heavy chain 12 (MYH12) gene to chromosome band 15q21

K. J. Moore, J. R. Testa, U. Francke, A. Milatovich, N. G. Copeland, Nancy A. Jenkins

Cancer Prevention and Control (CPC)

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Sequences encoding 1,235 bp of the human myosin heavy chain 12 (MYH12) gene have been cloned from a human brain cDNA library by PCR amplification. The human sequence is 95.8% identical to the mouse sequence at the amino acid level, indicating that the MYH12 gene has been evolutionarily well conserved. Somatic cell hybrid analysis and in situ hybridization place the MYH12 gene on human chromosome 15, at band q21, and extend distally the known region of chromosome 15 linkage homology on mouse chromosome 9.

Original language	English
Pages (from-to)	53-58
Number of pages	6
Journal	Cytogenetics and Cell Genetics
Volume	69
Issue number	1-2
DOIs	https://doi.org/10.1159/000133937
State	Published - 1995

Access to Document

10.1159/000133937

Cite this

@article{f036d7d35fa640efb7c4da669b88baae,

title = "Cloning and regional assignment of the human myosin heavy chain 12 (MYH12) gene to chromosome band 15q21",

abstract = "Sequences encoding 1,235 bp of the human myosin heavy chain 12 (MYH12) gene have been cloned from a human brain cDNA library by PCR amplification. The human sequence is 95.8% identical to the mouse sequence at the amino acid level, indicating that the MYH12 gene has been evolutionarily well conserved. Somatic cell hybrid analysis and in situ hybridization place the MYH12 gene on human chromosome 15, at band q21, and extend distally the known region of chromosome 15 linkage homology on mouse chromosome 9.",

author = "Moore, {K. J.} and Testa, {J. R.} and U. Francke and A. Milatovich and Copeland, {N. G.} and Jenkins, {Nancy A.}",

year = "1995",

doi = "10.1159/000133937",

language = "English",

volume = "69",

pages = "53--58",

journal = "Cytogenetics and Cell Genetics",

issn = "0301-0171",

publisher = "S. Karger AG",

number = "1-2",

}

TY - JOUR

T1 - Cloning and regional assignment of the human myosin heavy chain 12 (MYH12) gene to chromosome band 15q21

AU - Moore, K. J.

AU - Testa, J. R.

AU - Francke, U.

AU - Milatovich, A.

AU - Copeland, N. G.

AU - Jenkins, Nancy A.

PY - 1995

Y1 - 1995

N2 - Sequences encoding 1,235 bp of the human myosin heavy chain 12 (MYH12) gene have been cloned from a human brain cDNA library by PCR amplification. The human sequence is 95.8% identical to the mouse sequence at the amino acid level, indicating that the MYH12 gene has been evolutionarily well conserved. Somatic cell hybrid analysis and in situ hybridization place the MYH12 gene on human chromosome 15, at band q21, and extend distally the known region of chromosome 15 linkage homology on mouse chromosome 9.

AB - Sequences encoding 1,235 bp of the human myosin heavy chain 12 (MYH12) gene have been cloned from a human brain cDNA library by PCR amplification. The human sequence is 95.8% identical to the mouse sequence at the amino acid level, indicating that the MYH12 gene has been evolutionarily well conserved. Somatic cell hybrid analysis and in situ hybridization place the MYH12 gene on human chromosome 15, at band q21, and extend distally the known region of chromosome 15 linkage homology on mouse chromosome 9.

UR - http://www.scopus.com/inward/record.url?scp=0028836490&partnerID=8YFLogxK

U2 - 10.1159/000133937

DO - 10.1159/000133937

M3 - Article

C2 - 7835087

AN - SCOPUS:0028836490

SN - 0301-0171

VL - 69

SP - 53

EP - 58

JO - Cytogenetics and Cell Genetics

JF - Cytogenetics and Cell Genetics

IS - 1-2

ER -

Cloning and regional assignment of the human myosin heavy chain 12 (MYH12) gene to chromosome band 15q21

Abstract

Access to Document

Other files and links

Fingerprint

Cite this