Chromosome mapping of the mouse Akt2 gene and Akt2 pseudogene

D. A. Altomare; C. A. Kozak; G. Sonoda; J. R. Testa

doi:10.1159/000134426

Chromosome mapping of the mouse Akt2 gene and Akt2 pseudogene

D. A. Altomare, C. A. Kozak, G. Sonoda, J. R. Testa

Cancer Prevention and Control (CPC)

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Abstract

We previously reported the cloning of a murine cDNA encoding the protein-serine/threonine kinase Akt2, and we used this clone to map the Akt2 gene to mouse chromosome (MMU) 7B1 by fluorescence in situ hybridization. We now have cloned and partially sequenced a mouse Akt2 pseudogene. An analysis of two sets of multilocus crosses revealed that the Akt2 gene is closely linked to the Cyp2a locus in proximal MMU7. The Akt2 pseudogene was mapped to proximal MMU11 by both multilocus mapping and fluorescence in situ hybridization.

Original language	English
Pages (from-to)	248-251
Number of pages	4
Journal	Cytogenetics and Cell Genetics
Volume	74
Issue number	4
DOIs	https://doi.org/10.1159/000134426
State	Published - Jan 1 1996

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abstract = "We previously reported the cloning of a murine cDNA encoding the protein-serine/threonine kinase Akt2, and we used this clone to map the Akt2 gene to mouse chromosome (MMU) 7B1 by fluorescence in situ hybridization. We now have cloned and partially sequenced a mouse Akt2 pseudogene. An analysis of two sets of multilocus crosses revealed that the Akt2 gene is closely linked to the Cyp2a locus in proximal MMU7. The Akt2 pseudogene was mapped to proximal MMU11 by both multilocus mapping and fluorescence in situ hybridization.",

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AU - Kozak, C. A.

AU - Sonoda, G.

AU - Testa, J. R.

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AB - We previously reported the cloning of a murine cDNA encoding the protein-serine/threonine kinase Akt2, and we used this clone to map the Akt2 gene to mouse chromosome (MMU) 7B1 by fluorescence in situ hybridization. We now have cloned and partially sequenced a mouse Akt2 pseudogene. An analysis of two sets of multilocus crosses revealed that the Akt2 gene is closely linked to the Cyp2a locus in proximal MMU7. The Akt2 pseudogene was mapped to proximal MMU11 by both multilocus mapping and fluorescence in situ hybridization.

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Chromosome mapping of the mouse Akt2 gene and Akt2 pseudogene

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