Chromatin replication: TRANSmitting the histone code

Han Wen Chang, V. M. Studitsky

Research output: Contribution to journalArticlepeer-review

Abstract

Efficient overcoming of the nucleosomal barrier and accurate maintenance of associated histone marks during chromatin replication are essential for normal functioning of the cell. Recent studies revealed new protein factors and histone modifications contributing to overcoming the nucleosomal barrier, and suggested an important role for DNA looping in survival of the original histones during replication. These studies suggest new possible mechanisms for transmitting the histone code to next generations of cells.
Original languageEnglish
JournalJ Nat Sci
Volume3
Issue number2
StatePublished - 2017

Keywords

  • Chromatin histones nucleosome replication segregation

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