Choroidal metastasis from hepatocellular carcinoma, diagnosed by fine needle aspiration biopsy and treated by iodine-125 brachytherapy

Lalkrushna Malaviya; Carol L. Shields; Kiran Turaka; Hormoz Ehya; Jerry A. Shields

doi:10.1007/s00417-011-1626-8

Choroidal metastasis from hepatocellular carcinoma, diagnosed by fine needle aspiration biopsy and treated by iodine-125 brachytherapy

Lalkrushna Malaviya, Carol L. Shields, Kiran Turaka, Hormoz Ehya, Jerry A. Shields

Pathology

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4 Scopus citations

Abstract

Purpose: To report a rare case of choroidal metastasis from hepatocellular carcinoma. Methods: A 63-year-old man with known hepatocellular carcinoma (HCC) and treated clavicular metastasis noted reduced visual acuity in the right eye. He was found to have an amelanotic choroidal tumor measuring 18 x 14 x 9.3 mm and with retinal detachment. Fine needle aspiration biopsy confirmed metastatic HCC. Results: The choroidal metastasis was treated with 5 days of iodine-125 plaque brachytherapy (3500 cGy to apex). Tumor regression to 2.6 mm thickness with resolution of retinal detachment and preservation of visual acuity at 20/40 at the 4-month follow-up was documented. Conclusions: HCC metastasis to the choroid can be treated with focal plaque brachytherapy, with preservation of vision and quality of life.

Original language	English
Pages (from-to)	1095-1098
Number of pages	4
Journal	Graefe's Archive for Clinical and Experimental Ophthalmology
Volume	249
Issue number	7
DOIs	https://doi.org/10.1007/s00417-011-1626-8
State	Published - Jul 2011

Keywords

Choroid
Eye
Hepatocellular carcinoma
Liver
Metastasis
Plaque radiotherapy

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10.1007/s00417-011-1626-8

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title = "Choroidal metastasis from hepatocellular carcinoma, diagnosed by fine needle aspiration biopsy and treated by iodine-125 brachytherapy",

abstract = "Purpose: To report a rare case of choroidal metastasis from hepatocellular carcinoma. Methods: A 63-year-old man with known hepatocellular carcinoma (HCC) and treated clavicular metastasis noted reduced visual acuity in the right eye. He was found to have an amelanotic choroidal tumor measuring 18 x 14 x 9.3 mm and with retinal detachment. Fine needle aspiration biopsy confirmed metastatic HCC. Results: The choroidal metastasis was treated with 5 days of iodine-125 plaque brachytherapy (3500 cGy to apex). Tumor regression to 2.6 mm thickness with resolution of retinal detachment and preservation of visual acuity at 20/40 at the 4-month follow-up was documented. Conclusions: HCC metastasis to the choroid can be treated with focal plaque brachytherapy, with preservation of vision and quality of life.",

keywords = "Choroid, Eye, Hepatocellular carcinoma, Liver, Metastasis, Plaque radiotherapy",

author = "Lalkrushna Malaviya and Shields, {Carol L.} and Kiran Turaka and Hormoz Ehya and Shields, {Jerry A.}",

year = "2011",

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Choroidal metastasis from hepatocellular carcinoma, diagnosed by fine needle aspiration biopsy and treated by iodine-125 brachytherapy. / Malaviya, Lalkrushna; Shields, Carol L.; Turaka, Kiran et al.
In: Graefe's Archive for Clinical and Experimental Ophthalmology, Vol. 249, No. 7, 07.2011, p. 1095-1098.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Choroidal metastasis from hepatocellular carcinoma, diagnosed by fine needle aspiration biopsy and treated by iodine-125 brachytherapy

AU - Malaviya, Lalkrushna

AU - Shields, Carol L.

AU - Turaka, Kiran

AU - Ehya, Hormoz

AU - Shields, Jerry A.

PY - 2011/7

Y1 - 2011/7

N2 - Purpose: To report a rare case of choroidal metastasis from hepatocellular carcinoma. Methods: A 63-year-old man with known hepatocellular carcinoma (HCC) and treated clavicular metastasis noted reduced visual acuity in the right eye. He was found to have an amelanotic choroidal tumor measuring 18 x 14 x 9.3 mm and with retinal detachment. Fine needle aspiration biopsy confirmed metastatic HCC. Results: The choroidal metastasis was treated with 5 days of iodine-125 plaque brachytherapy (3500 cGy to apex). Tumor regression to 2.6 mm thickness with resolution of retinal detachment and preservation of visual acuity at 20/40 at the 4-month follow-up was documented. Conclusions: HCC metastasis to the choroid can be treated with focal plaque brachytherapy, with preservation of vision and quality of life.

AB - Purpose: To report a rare case of choroidal metastasis from hepatocellular carcinoma. Methods: A 63-year-old man with known hepatocellular carcinoma (HCC) and treated clavicular metastasis noted reduced visual acuity in the right eye. He was found to have an amelanotic choroidal tumor measuring 18 x 14 x 9.3 mm and with retinal detachment. Fine needle aspiration biopsy confirmed metastatic HCC. Results: The choroidal metastasis was treated with 5 days of iodine-125 plaque brachytherapy (3500 cGy to apex). Tumor regression to 2.6 mm thickness with resolution of retinal detachment and preservation of visual acuity at 20/40 at the 4-month follow-up was documented. Conclusions: HCC metastasis to the choroid can be treated with focal plaque brachytherapy, with preservation of vision and quality of life.

KW - Choroid

KW - Eye

KW - Hepatocellular carcinoma

KW - Liver

KW - Metastasis

KW - Plaque radiotherapy

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U2 - 10.1007/s00417-011-1626-8

DO - 10.1007/s00417-011-1626-8

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C2 - 21305314

SN - 0721-832X

VL - 249

SP - 1095

EP - 1098

JO - Graefe's Archive for Clinical and Experimental Ophthalmology

JF - Graefe's Archive for Clinical and Experimental Ophthalmology

IS - 7

ER -

Choroidal metastasis from hepatocellular carcinoma, diagnosed by fine needle aspiration biopsy and treated by iodine-125 brachytherapy

Abstract

Keywords

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