Choroidal melanoma in an African-American albino

S. Kheterpal; J. A. Shields; C. L. Shields; P. De Potter; H. Ehya; K. Y. Eng

doi:10.1016/S0002-9394(14)70396-4

Choroidal melanoma in an African-American albino

S. Kheterpal, J. A. Shields, C. L. Shields, P. De Potter, H. Ehya, K. Y. Eng

Pathology

Wills Eye Hospital

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

PURPOSE: To report the rare occurrence of choroidal melanoma in an African-American albino. METHODS: A 68-year-old African-American man with oculocutaneous albinism developed an amelanotic choroidal mass in his left eye. A transvitreal fine-needle aspiration biopsy was performed to confirm the diagnosis, and the patient was treated with iodine 125 plaque radiotherapy. RESULTS: The cytology of the needle biopsy showed spindle cells with nuclear atypia and prominent nucleoli. The cells showed positive immunoreactivity for HMB-45, supporting the diagnosis of choroidal melanoma. CONCLUSION: To our knowledge, this is the first reported case of a choroidal melanoma occurring in an African-American albino.

Original language	English
Pages (from-to)	901-903
Number of pages	3
Journal	American Journal of Ophthalmology
Volume	122
Issue number	6
DOIs	https://doi.org/10.1016/S0002-9394(14)70396-4
State	Published - 1996

Keywords

Aged
Albinism, Oculocutaneous/complications
Black or African American
Brachytherapy
Choroid Neoplasms/complications
Humans
Iodine Radioisotopes/therapeutic use
Male
Melanoma/complications

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10.1016/S0002-9394(14)70396-4

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title = "Choroidal melanoma in an African-American albino",

abstract = "PURPOSE: To report the rare occurrence of choroidal melanoma in an African-American albino. METHODS: A 68-year-old African-American man with oculocutaneous albinism developed an amelanotic choroidal mass in his left eye. A transvitreal fine-needle aspiration biopsy was performed to confirm the diagnosis, and the patient was treated with iodine 125 plaque radiotherapy. RESULTS: The cytology of the needle biopsy showed spindle cells with nuclear atypia and prominent nucleoli. The cells showed positive immunoreactivity for HMB-45, supporting the diagnosis of choroidal melanoma. CONCLUSION: To our knowledge, this is the first reported case of a choroidal melanoma occurring in an African-American albino.",

keywords = "Aged, Albinism, Oculocutaneous/complications, Black or African American, Brachytherapy, Choroid Neoplasms/complications, Humans, Iodine Radioisotopes/therapeutic use, Male, Melanoma/complications",

author = "S. Kheterpal and Shields, {J. A.} and Shields, {C. L.} and {De Potter}, P. and H. Ehya and Eng, {K. Y.}",

year = "1996",

doi = "10.1016/S0002-9394(14)70396-4",

language = "English",

volume = "122",

pages = "901--903",

journal = "American Journal of Ophthalmology",

issn = "0002-9394",

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T1 - Choroidal melanoma in an African-American albino

AU - Kheterpal, S.

AU - Shields, J. A.

AU - Shields, C. L.

AU - De Potter, P.

AU - Ehya, H.

AU - Eng, K. Y.

PY - 1996

Y1 - 1996

N2 - PURPOSE: To report the rare occurrence of choroidal melanoma in an African-American albino. METHODS: A 68-year-old African-American man with oculocutaneous albinism developed an amelanotic choroidal mass in his left eye. A transvitreal fine-needle aspiration biopsy was performed to confirm the diagnosis, and the patient was treated with iodine 125 plaque radiotherapy. RESULTS: The cytology of the needle biopsy showed spindle cells with nuclear atypia and prominent nucleoli. The cells showed positive immunoreactivity for HMB-45, supporting the diagnosis of choroidal melanoma. CONCLUSION: To our knowledge, this is the first reported case of a choroidal melanoma occurring in an African-American albino.

AB - PURPOSE: To report the rare occurrence of choroidal melanoma in an African-American albino. METHODS: A 68-year-old African-American man with oculocutaneous albinism developed an amelanotic choroidal mass in his left eye. A transvitreal fine-needle aspiration biopsy was performed to confirm the diagnosis, and the patient was treated with iodine 125 plaque radiotherapy. RESULTS: The cytology of the needle biopsy showed spindle cells with nuclear atypia and prominent nucleoli. The cells showed positive immunoreactivity for HMB-45, supporting the diagnosis of choroidal melanoma. CONCLUSION: To our knowledge, this is the first reported case of a choroidal melanoma occurring in an African-American albino.

KW - Aged

KW - Albinism, Oculocutaneous/complications

KW - Black or African American

KW - Brachytherapy

KW - Choroid Neoplasms/complications

KW - Humans

KW - Iodine Radioisotopes/therapeutic use

KW - Male

KW - Melanoma/complications

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JO - American Journal of Ophthalmology

JF - American Journal of Ophthalmology

IS - 6

ER -

Choroidal melanoma in an African-American albino

Abstract

Keywords

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