CD4 and CD8: Hogging All the Lck

Research output: Contribution to journalShort surveypeer-review

10 Scopus citations

Abstract

Specificity of T cell receptors (TCRs) to major histocompatibility complex (MHC) might be intrinsic or imposed by thymic selection. Van Laethem et al. (2007) propose that the sequestration of the kinase Lck by coreceptors prevents the selection of non-MHC-reactive TCRs.

Original languageEnglish
Pages (from-to)691-693
Number of pages3
JournalImmunity
Volume27
Issue number5
DOIs
StatePublished - Nov 26 2007

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