Abstract
Specificity of T cell receptors (TCRs) to major histocompatibility complex (MHC) might be intrinsic or imposed by thymic selection. Van Laethem et al. (2007) propose that the sequestration of the kinase Lck by coreceptors prevents the selection of non-MHC-reactive TCRs.
Original language | English |
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Pages (from-to) | 691-693 |
Number of pages | 3 |
Journal | Immunity |
Volume | 27 |
Issue number | 5 |
DOIs | |
State | Published - Nov 26 2007 |