Cancer stem cell immunoediting by IFNγ

Claudia Galassi, Lorenzo Galluzzi

Research output: Contribution to journalComment/debate

Abstract

The secretion of interferon gamma (IFNG, best known as IFNγ) by immune effector cells generally mediates potent anticancer effects. Recent data from Beziaud et al. demonstrate that—at least in some circumstances—IFNγ can edit the breast cancer microenvironment to promote stemness, disease progression and resistance to (immuno)therapy.

Original languageEnglish
Article number538
Pages (from-to)538
JournalCell Death and Disease
Volume14
Issue number8
DOIs
StatePublished - Aug 2023
Externally publishedYes

Keywords

  • Humans
  • Neoplasms

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