Cancer and the gut microbiota: An unexpected link

Laurence Zitvogel; Lorenzo Galluzzi; Sophie Viaud; Marie Vétizou; Romain Daillère; Miriam Merad; Guido Kroemer

doi:10.1126/scitranslmed.3010473

Cancer and the gut microbiota: An unexpected link

Laurence Zitvogel, Lorenzo Galluzzi, Sophie Viaud, Marie Vétizou, Romain Daillère, Miriam Merad, Guido Kroemer

Research output: Contribution to journal › Article › peer-review

400 Scopus citations

Abstract

Changes in the interactions among the gut microbiota, intestinal epithelium, and host immune system are associated with many diseases, including cancer. We discuss how environmental factors influence this cross-talk during oncogenesis and tumor progression and how manipulations of the gut microbiota might improve the clinical activity of anticancer agents.

Original language	English
Article number	271ps1
Journal	Science Translational Medicine
Volume	7
Issue number	271
DOIs	https://doi.org/10.1126/scitranslmed.3010473
State	Published - Jan 21 2015
Externally published	Yes

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title = "Cancer and the gut microbiota: An unexpected link",

abstract = "Changes in the interactions among the gut microbiota, intestinal epithelium, and host immune system are associated with many diseases, including cancer. We discuss how environmental factors influence this cross-talk during oncogenesis and tumor progression and how manipulations of the gut microbiota might improve the clinical activity of anticancer agents.",

author = "Laurence Zitvogel and Lorenzo Galluzzi and Sophie Viaud and Marie V{\'e}tizou and Romain Daill{\`e}re and Miriam Merad and Guido Kroemer",

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T2 - An unexpected link

AU - Zitvogel, Laurence

AU - Galluzzi, Lorenzo

AU - Viaud, Sophie

AU - Vétizou, Marie

AU - Daillère, Romain

AU - Merad, Miriam

AU - Kroemer, Guido

PY - 2015/1/21

Y1 - 2015/1/21

N2 - Changes in the interactions among the gut microbiota, intestinal epithelium, and host immune system are associated with many diseases, including cancer. We discuss how environmental factors influence this cross-talk during oncogenesis and tumor progression and how manipulations of the gut microbiota might improve the clinical activity of anticancer agents.

AB - Changes in the interactions among the gut microbiota, intestinal epithelium, and host immune system are associated with many diseases, including cancer. We discuss how environmental factors influence this cross-talk during oncogenesis and tumor progression and how manipulations of the gut microbiota might improve the clinical activity of anticancer agents.

UR - https://www.scopus.com/pages/publications/84921742288

U2 - 10.1126/scitranslmed.3010473

DO - 10.1126/scitranslmed.3010473

M3 - Article

C2 - 25609166

AN - SCOPUS:84921742288

SN - 1946-6234

VL - 7

JO - Science Translational Medicine

JF - Science Translational Medicine

IS - 271

M1 - 271ps1

ER -

Cancer and the gut microbiota: An unexpected link

Abstract

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