BRCA-related ovarian carcinoma: Another piece of the puzzle?

Stephen C. Rubin

doi:10.1002/cncr.11341

BRCA-related ovarian carcinoma: Another piece of the puzzle?

Stephen C. Rubin

Surgery

University of Pennsylvania

Research output: Contribution to journal › Review article › peer-review

15 Scopus citations

Abstract

The author comments on a report in this issue of Cancer by investigators who used clinical response endpoints and chemoresistance testing to confirm the improved survival of women with hereditary ovarian carcinoma compared with women who had sporadic ovarian carcinoma. The possible use of BRCA mutation status to improve patient care, the future of translational research, and the difficulties in proceeding with large-scale prospective trials are among the topics discussed.

Original language	English
Pages (from-to)	2127-2129
Number of pages	3
Journal	Cancer
Volume	97
Issue number	9
DOIs	https://doi.org/10.1002/cncr.11341
State	Published - May 1 2003

Keywords

BRCA1 Protein/genetics
BRCA2 Protein/genetics
Disease-Free Survival
Female
Germ-Line Mutation
Humans
Ovarian Neoplasms/genetics
Survival Rate

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10.1002/cncr.11341

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AB - The author comments on a report in this issue of Cancer by investigators who used clinical response endpoints and chemoresistance testing to confirm the improved survival of women with hereditary ovarian carcinoma compared with women who had sporadic ovarian carcinoma. The possible use of BRCA mutation status to improve patient care, the future of translational research, and the difficulties in proceeding with large-scale prospective trials are among the topics discussed.

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KW - BRCA2 Protein/genetics

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KW - Germ-Line Mutation

KW - Humans

KW - Ovarian Neoplasms/genetics

KW - Survival Rate

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BRCA-related ovarian carcinoma: Another piece of the puzzle?

Abstract

Keywords

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