BeoBLAST: Distributed BLAST and PSI-BLAST on a Beowulf cluster

J. D. Grant; R. L. Dunbrack; Frank J. Manion; Michael F. Ochs

doi:10.1093/bioinformatics/18.5.765

BeoBLAST: Distributed BLAST and PSI-BLAST on a Beowulf cluster

J. D. Grant, R. L. Dunbrack, Frank J. Manion, Michael F. Ochs

Cancer Signaling and Microenvironment (CSM)

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

Summary: BeoBLAST is an integrated software package that handles user requests and distributes BLAST and PSI-BLAST searches to nodes of a Beowulf cluster, thus providing a simple way to implement a scalable BLAST system on top of relatively inexpensive computer clusters. Additionally, BeoBLAST offers a number of novel search features through it's web interface, including the ability to perform simultaneous searches of multiple databases with multiple queries, and the ability to start a search using the PSSM generated from a previous PSI-BLAST search on a different database. The underlying system can also handle automated querying for high throughput work.

Original language	English
Pages (from-to)	765-766
Number of pages	2
Journal	Bioinformatics
Volume	18
Issue number	5
DOIs	https://doi.org/10.1093/bioinformatics/18.5.765
State	Published - 2002

Keywords

Computer Communication Networks
Computing Methodologies
Database Management Systems
Databases, Genetic
Information Storage and Retrieval/methods
Internet
National Library of Medicine (U.S.)
Sequence Analysis
United States

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10.1093/bioinformatics/18.5.765

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abstract = "Summary: BeoBLAST is an integrated software package that handles user requests and distributes BLAST and PSI-BLAST searches to nodes of a Beowulf cluster, thus providing a simple way to implement a scalable BLAST system on top of relatively inexpensive computer clusters. Additionally, BeoBLAST offers a number of novel search features through it's web interface, including the ability to perform simultaneous searches of multiple databases with multiple queries, and the ability to start a search using the PSSM generated from a previous PSI-BLAST search on a different database. The underlying system can also handle automated querying for high throughput work.",

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AU - Dunbrack, R. L.

AU - Manion, Frank J.

AU - Ochs, Michael F.

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KW - National Library of Medicine (U.S.)

KW - Sequence Analysis

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BeoBLAST: Distributed BLAST and PSI-BLAST on a Beowulf cluster

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Keywords

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