Bacterial Invasion: Linking Autophagy and Innate Immunity

Lorenzo Galluzzi; Oliver Kepp; Laurence Zitvogel; Guido Kroemer

doi:10.1016/j.cub.2009.12.016

Bacterial Invasion: Linking Autophagy and Innate Immunity

Lorenzo Galluzzi, Oliver Kepp, Laurence Zitvogel, Guido Kroemer

Research output: Contribution to journal › Short survey › peer-review

13 Scopus citations

Abstract

Crohn's disease is a chronic inflammatory bowel disorder that has been associated with polymorphisms in the genes encoding the pattern-recognition receptor NOD2 and the autophagic regulator ATG16L1. A new study demonstrates that NOD2 recruits ATG16L1 at bacterial entry sites, thereby bridging innate immunity and autophagy.

Original language	English
Pages (from-to)	R106-R108
Journal	Current Biology
Volume	20
Issue number	3
DOIs	https://doi.org/10.1016/j.cub.2009.12.016
State	Published - Feb 9 2010
Externally published	Yes

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10.1016/j.cub.2009.12.016

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title = "Bacterial Invasion: Linking Autophagy and Innate Immunity",

abstract = "Crohn's disease is a chronic inflammatory bowel disorder that has been associated with polymorphisms in the genes encoding the pattern-recognition receptor NOD2 and the autophagic regulator ATG16L1. A new study demonstrates that NOD2 recruits ATG16L1 at bacterial entry sites, thereby bridging innate immunity and autophagy.",

author = "Lorenzo Galluzzi and Oliver Kepp and Laurence Zitvogel and Guido Kroemer",

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T1 - Bacterial Invasion

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AU - Galluzzi, Lorenzo

AU - Kepp, Oliver

AU - Zitvogel, Laurence

AU - Kroemer, Guido

PY - 2010/2/9

Y1 - 2010/2/9

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AB - Crohn's disease is a chronic inflammatory bowel disorder that has been associated with polymorphisms in the genes encoding the pattern-recognition receptor NOD2 and the autophagic regulator ATG16L1. A new study demonstrates that NOD2 recruits ATG16L1 at bacterial entry sites, thereby bridging innate immunity and autophagy.

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U2 - 10.1016/j.cub.2009.12.016

DO - 10.1016/j.cub.2009.12.016

M3 - Short survey

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AN - SCOPUS:75749084029

SN - 0960-9822

VL - 20

SP - R106-R108

JO - Current Biology

JF - Current Biology

IS - 3

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Bacterial Invasion: Linking Autophagy and Innate Immunity

Abstract

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