Atypical squamous cells in papanicolaou smears

Gregory L. Davis, Enrique Hernandez, Jane L. Davis, Kunio Miyazawa

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58 Scopus citations

Abstract

Between 1980 and 1984, 406 patients were referred to Tripler Army Medical Center's cervical clinic for the evaluation of atypical squamous cells in a Papanicolaou smear. Their evaluation included repeating the smear, colposcopy in all cases, colposcopically directed biopsies, and/or endocervical curettage in 70%. The results of the repeat Papanicolaou smear in 400 patients were 274 (68.5%) negative, 77 (19%) atypical squamous cells, 40 (10%) cervical intraepithelial neoplasia (CIN) 1, seven (2%) CIN 2, and two (0.5%) CIN 3. No invasive cancer was detected. Dysplasia was documented histopathologically in 18.7%, but a repeat smear was reported as negative in 10.9% of patients with biopsyproven dysplasia. A Papanicolaou smear report of atypical squamous cells should not be considered normal, and further evaluation of the patient is required. If colposcopy is impractical, serial follow-up smears are recommended.

Original languageEnglish
Pages (from-to)43-46
Number of pages4
JournalObstetrics and Gynecology
Volume69
Issue number1
StatePublished - Jan 1987

Keywords

  • Biopsy
  • Colposcopy
  • Cytological Techniques
  • Dilatation and Curettage
  • Female
  • Humans
  • Mucous Membrane/cytology
  • Papanicolaou Test
  • Uterine Cervical Dysplasia/diagnosis
  • Uterine Cervical Neoplasms/diagnosis
  • Vaginal Smears

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