Applications of a pet device with 1.5 MM FWHM intrinsic spatial resolution to breast cancer imaging

Irving Weinberg; David Beylin; Steve Yarnall; Edward Anashkin; Pavel Stepanov; Sevgei Dolinsky; Valera Zavarzin; William Peter; Kathrin Lauckner; Kathryn Morton; Rita Freimanis; Nadia Lesko; Edward Levine; Nancy Perrier; Judy Lovelace; Kim Geisinger; Rodney Williams; Scott Wollenweber; Deepa Narayanan; Mohan Doss; Jean Hummel; Elin Sigurdson; Kathryn Evers; Michael Torosian; Lee Adler

Applications of a pet device with 1.5 MM FWHM intrinsic spatial resolution to breast cancer imaging

Irving Weinberg, David Beylin, Steve Yarnall, Edward Anashkin, Pavel Stepanov, Sevgei Dolinsky, Valera Zavarzin, William Peter, Kathrin Lauckner, Kathryn Morton, Rita Freimanis, Nadia Lesko, Edward Levine, Nancy Perrier, Judy Lovelace, Kim Geisinger, Rodney Williams, Scott Wollenweber, Deepa Narayanan, Mohan DossJean Hummel, Elin Sigurdson, Kathryn Evers, Michael Torosian, Lee Adler

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

12 Scopus citations

Abstract

Operation of a high resolution compact clinical PET Scanner (PEM Flex™) device as a breast scanner is described. The device features high spatial resolution (1.5 mm FWHM intrinsic resolution) as a result of small crystals and compact position-sensitive photomultipliers. The compactness of the system allows it to reside within a stereotactic x-ray mammography unit, or as a separate standalone system capable of breast compression. The gamma rays are detected for a volumetric reconstruction by two heads, each of which contains 2,028 2 mm by 2 mm by 10 mm lutetium-containing crystals. The heads travel within x-ray transparent compression paddles. A window is provided in one of the paddles for direct correlation with ultrasound transducers and for interventional access. To enable real-time interventions, images are reconstructed and displayed while the detectors are still acquiring data. The maximum-likelihood reconstruction provides quantitative images with three-fold improved contrast as compared to simple back-projections.

Original language	English
Title of host publication	2004 2nd IEEE International Symposium on Biomedical Imaging
Subtitle of host publication	Macro to Nano
Pages	1396-1399
Number of pages	4
State	Published - 2004
Event	2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano - Arlington, VA, United States Duration: Apr 15 2004 → Apr 18 2004

Publication series

Name	2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Volume	2

Conference

Conference	2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Country/Territory	United States
City	Arlington, VA
Period	04/15/04 → 04/18/04

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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Weinberg, I., Beylin, D., Yarnall, S., Anashkin, E., Stepanov, P., Dolinsky, S., Zavarzin, V., Peter, W., Lauckner, K., Morton, K., Freimanis, R., Lesko, N., Levine, E., Perrier, N., Lovelace, J., Geisinger, K., Williams, R., Wollenweber, S., Narayanan, D., ... Adler, L. (2004). Applications of a pet device with 1.5 MM FWHM intrinsic spatial resolution to breast cancer imaging. In 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano (pp. 1396-1399). (2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano; Vol. 2).

@inproceedings{5628231cc9cd47b994dcd9220d363d39,

title = "Applications of a pet device with 1.5 MM FWHM intrinsic spatial resolution to breast cancer imaging",

abstract = "Operation of a high resolution compact clinical PET Scanner (PEM Flex{\texttrademark}) device as a breast scanner is described. The device features high spatial resolution (1.5 mm FWHM intrinsic resolution) as a result of small crystals and compact position-sensitive photomultipliers. The compactness of the system allows it to reside within a stereotactic x-ray mammography unit, or as a separate standalone system capable of breast compression. The gamma rays are detected for a volumetric reconstruction by two heads, each of which contains 2,028 2 mm by 2 mm by 10 mm lutetium-containing crystals. The heads travel within x-ray transparent compression paddles. A window is provided in one of the paddles for direct correlation with ultrasound transducers and for interventional access. To enable real-time interventions, images are reconstructed and displayed while the detectors are still acquiring data. The maximum-likelihood reconstruction provides quantitative images with three-fold improved contrast as compared to simple back-projections.",

author = "Irving Weinberg and David Beylin and Steve Yarnall and Edward Anashkin and Pavel Stepanov and Sevgei Dolinsky and Valera Zavarzin and William Peter and Kathrin Lauckner and Kathryn Morton and Rita Freimanis and Nadia Lesko and Edward Levine and Nancy Perrier and Judy Lovelace and Kim Geisinger and Rodney Williams and Scott Wollenweber and Deepa Narayanan and Mohan Doss and Jean Hummel and Elin Sigurdson and Kathryn Evers and Michael Torosian and Lee Adler",

year = "2004",

language = "English",

isbn = "0780383885",

series = "2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano",

pages = "1396--1399",

booktitle = "2004 2nd IEEE International Symposium on Biomedical Imaging",

note = "2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano ; Conference date: 15-04-2004 Through 18-04-2004",

}

Weinberg, I, Beylin, D, Yarnall, S, Anashkin, E, Stepanov, P, Dolinsky, S, Zavarzin, V, Peter, W, Lauckner, K, Morton, K, Freimanis, R, Lesko, N, Levine, E, Perrier, N, Lovelace, J, Geisinger, K, Williams, R, Wollenweber, S, Narayanan, D, Doss, M, Hummel, J, Sigurdson, E, Evers, K, Torosian, M & Adler, L 2004, Applications of a pet device with 1.5 MM FWHM intrinsic spatial resolution to breast cancer imaging. in 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano. 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano, vol. 2, pp. 1396-1399, 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano, Arlington, VA, United States, 04/15/04.

Applications of a pet device with 1.5 MM FWHM intrinsic spatial resolution to breast cancer imaging. / Weinberg, Irving; Beylin, David; Yarnall, Steve et al.
2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano. 2004. p. 1396-1399 (2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano; Vol. 2).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Applications of a pet device with 1.5 MM FWHM intrinsic spatial resolution to breast cancer imaging

AU - Weinberg, Irving

AU - Beylin, David

AU - Yarnall, Steve

AU - Anashkin, Edward

AU - Stepanov, Pavel

AU - Dolinsky, Sevgei

AU - Zavarzin, Valera

AU - Peter, William

AU - Lauckner, Kathrin

AU - Morton, Kathryn

AU - Freimanis, Rita

AU - Lesko, Nadia

AU - Levine, Edward

AU - Perrier, Nancy

AU - Lovelace, Judy

AU - Geisinger, Kim

AU - Williams, Rodney

AU - Wollenweber, Scott

AU - Narayanan, Deepa

AU - Doss, Mohan

AU - Hummel, Jean

AU - Sigurdson, Elin

AU - Evers, Kathryn

AU - Torosian, Michael

AU - Adler, Lee

PY - 2004

Y1 - 2004

N2 - Operation of a high resolution compact clinical PET Scanner (PEM Flex™) device as a breast scanner is described. The device features high spatial resolution (1.5 mm FWHM intrinsic resolution) as a result of small crystals and compact position-sensitive photomultipliers. The compactness of the system allows it to reside within a stereotactic x-ray mammography unit, or as a separate standalone system capable of breast compression. The gamma rays are detected for a volumetric reconstruction by two heads, each of which contains 2,028 2 mm by 2 mm by 10 mm lutetium-containing crystals. The heads travel within x-ray transparent compression paddles. A window is provided in one of the paddles for direct correlation with ultrasound transducers and for interventional access. To enable real-time interventions, images are reconstructed and displayed while the detectors are still acquiring data. The maximum-likelihood reconstruction provides quantitative images with three-fold improved contrast as compared to simple back-projections.

AB - Operation of a high resolution compact clinical PET Scanner (PEM Flex™) device as a breast scanner is described. The device features high spatial resolution (1.5 mm FWHM intrinsic resolution) as a result of small crystals and compact position-sensitive photomultipliers. The compactness of the system allows it to reside within a stereotactic x-ray mammography unit, or as a separate standalone system capable of breast compression. The gamma rays are detected for a volumetric reconstruction by two heads, each of which contains 2,028 2 mm by 2 mm by 10 mm lutetium-containing crystals. The heads travel within x-ray transparent compression paddles. A window is provided in one of the paddles for direct correlation with ultrasound transducers and for interventional access. To enable real-time interventions, images are reconstructed and displayed while the detectors are still acquiring data. The maximum-likelihood reconstruction provides quantitative images with three-fold improved contrast as compared to simple back-projections.

UR - http://www.scopus.com/inward/record.url?scp=20244387846&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:20244387846

SN - 0780383885

SN - 9780780383883

T3 - 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano

SP - 1396

EP - 1399

BT - 2004 2nd IEEE International Symposium on Biomedical Imaging

T2 - 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano

Y2 - 15 April 2004 through 18 April 2004

ER -

Applications of a pet device with 1.5 MM FWHM intrinsic spatial resolution to breast cancer imaging

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