An intraoperative real-time sleeved seed technique for permanent prostate brachytherapy

Navesh K. Sharma; Randi J. Cohen; Thomas N. Eade; Mark K. Buyyounouski; Robert G. Uzzo; Jinsheng Li; Kevin Crawford; David Y.T. Chen; Shawn McNeeley; Eric M. Horwitz

doi:10.1016/j.brachy.2009.08.004

An intraoperative real-time sleeved seed technique for permanent prostate brachytherapy

Navesh K. Sharma, Randi J. Cohen, Thomas N. Eade, Mark K. Buyyounouski, Robert G. Uzzo, Jinsheng Li, Kevin Crawford, David Y.T. Chen, Shawn McNeeley, Eric M. Horwitz

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Purpose: To describe a novel technique that integrates customized sleeved seed production to reduce seed migration using preloaded needles with real-time intraoperative dosimetric planning for patients treated with iodine-125 (I-125) permanent prostate seed implants. Methods and Materials: Customized seed-spacer sequences were calculated for patients in real time based on an intraoperative transrectal ultrasound-guided volume study. Using a Fox Chase Cancer Center modified Best Iodine-125 seed loader (Best Medical, Springfield, VA), the seeds and spacers were inserted into a hollow suture material (sleeve) and then loaded into the implant needles. Needles were placed sequentially under transrectal ultrasound guidance with sagittal plane visualization of the dropped sleeved seeds. Results: This technique was successfully implemented allowing intraoperative planning to be combined with real-time sleeved seed production. Conclusions: The use of sleeves for seeds combined with real-time intraoperative planning allowed for the intraoperative customization of implants with the practical advantages of linked seeds.

Original language	English
Pages (from-to)	126-130
Number of pages	5
Journal	Brachytherapy
Volume	9
Issue number	2
DOIs	https://doi.org/10.1016/j.brachy.2009.08.004
State	Published - Apr 2010

Keywords

I-125
Intraoperative planning
Low-dose-rate brachytherapy
Prostate
Prostate cancer
Sleeved seeds

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10.1016/j.brachy.2009.08.004

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@article{de295546374d41debcc4abc5b8ad901b,

title = "An intraoperative real-time sleeved seed technique for permanent prostate brachytherapy",

abstract = "Purpose: To describe a novel technique that integrates customized sleeved seed production to reduce seed migration using preloaded needles with real-time intraoperative dosimetric planning for patients treated with iodine-125 (I-125) permanent prostate seed implants. Methods and Materials: Customized seed-spacer sequences were calculated for patients in real time based on an intraoperative transrectal ultrasound-guided volume study. Using a Fox Chase Cancer Center modified Best Iodine-125 seed loader (Best Medical, Springfield, VA), the seeds and spacers were inserted into a hollow suture material (sleeve) and then loaded into the implant needles. Needles were placed sequentially under transrectal ultrasound guidance with sagittal plane visualization of the dropped sleeved seeds. Results: This technique was successfully implemented allowing intraoperative planning to be combined with real-time sleeved seed production. Conclusions: The use of sleeves for seeds combined with real-time intraoperative planning allowed for the intraoperative customization of implants with the practical advantages of linked seeds.",

keywords = "I-125, Intraoperative planning, Low-dose-rate brachytherapy, Prostate, Prostate cancer, Sleeved seeds",

author = "Sharma, {Navesh K.} and Cohen, {Randi J.} and Eade, {Thomas N.} and Buyyounouski, {Mark K.} and Uzzo, {Robert G.} and Jinsheng Li and Kevin Crawford and Chen, {David Y.T.} and Shawn McNeeley and Horwitz, {Eric M.}",

year = "2010",

month = apr,

doi = "10.1016/j.brachy.2009.08.004",

language = "English",

volume = "9",

pages = "126--130",

journal = "Brachytherapy",

issn = "1538-4721",

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AU - Sharma, Navesh K.

AU - Cohen, Randi J.

AU - Eade, Thomas N.

AU - Buyyounouski, Mark K.

AU - Uzzo, Robert G.

AU - Li, Jinsheng

AU - Crawford, Kevin

AU - Chen, David Y.T.

AU - McNeeley, Shawn

AU - Horwitz, Eric M.

PY - 2010/4

Y1 - 2010/4

N2 - Purpose: To describe a novel technique that integrates customized sleeved seed production to reduce seed migration using preloaded needles with real-time intraoperative dosimetric planning for patients treated with iodine-125 (I-125) permanent prostate seed implants. Methods and Materials: Customized seed-spacer sequences were calculated for patients in real time based on an intraoperative transrectal ultrasound-guided volume study. Using a Fox Chase Cancer Center modified Best Iodine-125 seed loader (Best Medical, Springfield, VA), the seeds and spacers were inserted into a hollow suture material (sleeve) and then loaded into the implant needles. Needles were placed sequentially under transrectal ultrasound guidance with sagittal plane visualization of the dropped sleeved seeds. Results: This technique was successfully implemented allowing intraoperative planning to be combined with real-time sleeved seed production. Conclusions: The use of sleeves for seeds combined with real-time intraoperative planning allowed for the intraoperative customization of implants with the practical advantages of linked seeds.

AB - Purpose: To describe a novel technique that integrates customized sleeved seed production to reduce seed migration using preloaded needles with real-time intraoperative dosimetric planning for patients treated with iodine-125 (I-125) permanent prostate seed implants. Methods and Materials: Customized seed-spacer sequences were calculated for patients in real time based on an intraoperative transrectal ultrasound-guided volume study. Using a Fox Chase Cancer Center modified Best Iodine-125 seed loader (Best Medical, Springfield, VA), the seeds and spacers were inserted into a hollow suture material (sleeve) and then loaded into the implant needles. Needles were placed sequentially under transrectal ultrasound guidance with sagittal plane visualization of the dropped sleeved seeds. Results: This technique was successfully implemented allowing intraoperative planning to be combined with real-time sleeved seed production. Conclusions: The use of sleeves for seeds combined with real-time intraoperative planning allowed for the intraoperative customization of implants with the practical advantages of linked seeds.

KW - I-125

KW - Intraoperative planning

KW - Low-dose-rate brachytherapy

KW - Prostate

KW - Prostate cancer

KW - Sleeved seeds

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DO - 10.1016/j.brachy.2009.08.004

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SN - 1538-4721

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SP - 126

EP - 130

JO - Brachytherapy

JF - Brachytherapy

IS - 2

ER -

An intraoperative real-time sleeved seed technique for permanent prostate brachytherapy

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Keywords

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