Abstract
A recurrent theme in molecular biology is 'action at a distance' along DNA. Why can some regulatory DNA sequences (enhancers) work at a great distance from the target of regulation? As one possible solution to this question we shall consider an allosteric mechanism of enhancer action focused on eukaryotic transcriptional enhancers.
Original language | English |
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Pages (from-to) | 5-7 |
Number of pages | 3 |
Journal | FEBS Letters |
Volume | 280 |
Issue number | 1 |
DOIs | |
State | Published - Mar 11 1991 |
Keywords
- Allosteric action
- Enhancer and 'promoter' element
- Eukaryotic enhancer
- Stable initiation complex