Allosteric mechanism of enhancer action?

Research output: Contribution to journalArticlepeer-review

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Abstract

A recurrent theme in molecular biology is 'action at a distance' along DNA. Why can some regulatory DNA sequences (enhancers) work at a great distance from the target of regulation? As one possible solution to this question we shall consider an allosteric mechanism of enhancer action focused on eukaryotic transcriptional enhancers.

Original languageEnglish
Pages (from-to)5-7
Number of pages3
JournalFEBS Letters
Volume280
Issue number1
DOIs
StatePublished - Mar 11 1991

Keywords

  • Allosteric action
  • Enhancer and 'promoter' element
  • Eukaryotic enhancer
  • Stable initiation complex

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