Adult Cancer Pain, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology

Robert A. Swarm; Jeanie M. Youngwerth; Julia L. Agne; Magdalena Anitescu; Madhuri Are; Sorin Buga; Taylor Butler; Marcin Chwistek; James Cleary; David Copenhaver; Christopher Coyne; David Craig; Heidi Finnes; Heather Greenlee; Mona Gupta; Eric Hansen; Saba Javed; Enas Kandil; Sean Mackey; Andrew Mcdonald; Kathryn Mcgrath; Natalie Moryl; Suzanne Nesbit; Michael Noonan; Joseph Norris Jr; Judith A. Paice; Elizabeth Prsic; Michael W. Rabow; Elizabeth Rickerson; Jill Sindt; Michael Smith; Kevin Vorenkamp; Justine Yang Bruce; Sun Yoo; Rebecca Cunningham; Lisa A. Gurski; Frankie Jones

doi:10.6004/jnccn.2025.0032

Adult Cancer Pain, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology

Robert A. Swarm, Jeanie M. Youngwerth, Julia L. Agne, Magdalena Anitescu, Madhuri Are, Sorin Buga, Taylor Butler, Marcin Chwistek, James Cleary, David Copenhaver, Christopher Coyne, David Craig, Heidi Finnes, Heather Greenlee, Mona Gupta, Eric Hansen, Saba Javed, Enas Kandil, Sean Mackey, Andrew McdonaldKathryn Mcgrath, Natalie Moryl, Suzanne Nesbit, Michael Noonan, Joseph Norris Jr, Judith A. Paice, Elizabeth Prsic, Michael W. Rabow, Elizabeth Rickerson, Jill Sindt, Michael Smith, Kevin Vorenkamp, Justine Yang Bruce, Sun Yoo, Rebecca Cunningham, Lisa A. Gurski, Frankie Jones

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Adult Cancer Pain provide recommendations for the comprehensive management of pain in patients with cancer. This article will focus on methods for screening for pain, safe and appropriate prescription of opioid and miscellaneous analgesics, and the optimization of nonpharmacologic interventions including integrative and interventional strategies for treatment of cancer-related pain. Additionally, the NCCN Guidelines discuss methods for the safe reduction of opioids when appropriate, as well as techniques for encouraging the judicious use of opioids. The complete version of the NCCN Guidelines for Adult Cancer Pain addresses additional issues that are not covered here, including management of pain during a pain crisis, management of procedure-related pain and anxiety, pain management for cancer survivors, and the use of nonopioid and adjuvant analgesics for cancer-related pain.

Original language	English
Article number	e250032
Number of pages	25
Journal	Journal of the National Comprehensive Cancer Network
Volume	23
Issue number	7
DOIs	https://doi.org/10.6004/jnccn.2025.0032
State	Published - Jul 2025

Keywords

Adult
Analgesics, Opioid/therapeutic use
Cancer Pain/diagnosis
Humans
Medical Oncology/standards
Neoplasms/complications
Pain Management/methods

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.6004/jnccn.2025.0032

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Swarm, R. A., Youngwerth, J. M., Agne, J. L., Anitescu, M., Are, M., Buga, S., Butler, T., Chwistek, M., Cleary, J., Copenhaver, D., Coyne, C., Craig, D., Finnes, H., Greenlee, H., Gupta, M., Hansen, E., Javed, S., Kandil, E., Mackey, S., ... Jones, F. (2025). Adult Cancer Pain, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology. Journal of the National Comprehensive Cancer Network, 23(7), Article e250032. https://doi.org/10.6004/jnccn.2025.0032

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title = "Adult Cancer Pain, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology",

abstract = "The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Adult Cancer Pain provide recommendations for the comprehensive management of pain in patients with cancer. This article will focus on methods for screening for pain, safe and appropriate prescription of opioid and miscellaneous analgesics, and the optimization of nonpharmacologic interventions including integrative and interventional strategies for treatment of cancer-related pain. Additionally, the NCCN Guidelines discuss methods for the safe reduction of opioids when appropriate, as well as techniques for encouraging the judicious use of opioids. The complete version of the NCCN Guidelines for Adult Cancer Pain addresses additional issues that are not covered here, including management of pain during a pain crisis, management of procedure-related pain and anxiety, pain management for cancer survivors, and the use of nonopioid and adjuvant analgesics for cancer-related pain.",

keywords = "Adult, Analgesics, Opioid/therapeutic use, Cancer Pain/diagnosis, Humans, Medical Oncology/standards, Neoplasms/complications, Pain Management/methods",

author = "Swarm, \{Robert A.\} and Youngwerth, \{Jeanie M.\} and Agne, \{Julia L.\} and Magdalena Anitescu and Madhuri Are and Sorin Buga and Taylor Butler and Marcin Chwistek and James Cleary and David Copenhaver and Christopher Coyne and David Craig and Heidi Finnes and Heather Greenlee and Mona Gupta and Eric Hansen and Saba Javed and Enas Kandil and Sean Mackey and Andrew Mcdonald and Kathryn Mcgrath and Natalie Moryl and Suzanne Nesbit and Michael Noonan and \{Norris Jr\}, Joseph and Paice, \{Judith A.\} and Elizabeth Prsic and Rabow, \{Michael W.\} and Elizabeth Rickerson and Jill Sindt and Michael Smith and Kevin Vorenkamp and Bruce, \{Justine Yang\} and Sun Yoo and Rebecca Cunningham and Gurski, \{Lisa A.\} and Frankie Jones",

year = "2025",

month = jul,

doi = "10.6004/jnccn.2025.0032",

language = "English",

volume = "23",

journal = "Journal of the National Comprehensive Cancer Network",

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Swarm, RA, Youngwerth, JM, Agne, JL, Anitescu, M, Are, M, Buga, S, Butler, T, Chwistek, M, Cleary, J, Copenhaver, D, Coyne, C, Craig, D, Finnes, H, Greenlee, H, Gupta, M, Hansen, E, Javed, S, Kandil, E, Mackey, S, Mcdonald, A, Mcgrath, K, Moryl, N, Nesbit, S, Noonan, M, Norris Jr, J, Paice, JA, Prsic, E, Rabow, MW, Rickerson, E, Sindt, J, Smith, M, Vorenkamp, K, Bruce, JY, Yoo, S, Cunningham, R, Gurski, LA & Jones, F 2025, 'Adult Cancer Pain, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology', Journal of the National Comprehensive Cancer Network, vol. 23, no. 7, e250032. https://doi.org/10.6004/jnccn.2025.0032

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T1 - Adult Cancer Pain, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology

AU - Swarm, Robert A.

AU - Youngwerth, Jeanie M.

AU - Agne, Julia L.

AU - Anitescu, Magdalena

AU - Are, Madhuri

AU - Buga, Sorin

AU - Butler, Taylor

AU - Chwistek, Marcin

AU - Cleary, James

AU - Copenhaver, David

AU - Coyne, Christopher

AU - Craig, David

AU - Finnes, Heidi

AU - Greenlee, Heather

AU - Gupta, Mona

AU - Hansen, Eric

AU - Javed, Saba

AU - Kandil, Enas

AU - Mackey, Sean

AU - Mcdonald, Andrew

AU - Mcgrath, Kathryn

AU - Moryl, Natalie

AU - Nesbit, Suzanne

AU - Noonan, Michael

AU - Norris Jr, Joseph

AU - Paice, Judith A.

AU - Prsic, Elizabeth

AU - Rabow, Michael W.

AU - Rickerson, Elizabeth

AU - Sindt, Jill

AU - Smith, Michael

AU - Vorenkamp, Kevin

AU - Bruce, Justine Yang

AU - Yoo, Sun

AU - Cunningham, Rebecca

AU - Gurski, Lisa A.

AU - Jones, Frankie

PY - 2025/7

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N2 - The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Adult Cancer Pain provide recommendations for the comprehensive management of pain in patients with cancer. This article will focus on methods for screening for pain, safe and appropriate prescription of opioid and miscellaneous analgesics, and the optimization of nonpharmacologic interventions including integrative and interventional strategies for treatment of cancer-related pain. Additionally, the NCCN Guidelines discuss methods for the safe reduction of opioids when appropriate, as well as techniques for encouraging the judicious use of opioids. The complete version of the NCCN Guidelines for Adult Cancer Pain addresses additional issues that are not covered here, including management of pain during a pain crisis, management of procedure-related pain and anxiety, pain management for cancer survivors, and the use of nonopioid and adjuvant analgesics for cancer-related pain.

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KW - Adult

KW - Analgesics, Opioid/therapeutic use

KW - Cancer Pain/diagnosis

KW - Humans

KW - Medical Oncology/standards

KW - Neoplasms/complications

KW - Pain Management/methods

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DO - 10.6004/jnccn.2025.0032

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SN - 1540-1405

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JO - Journal of the National Comprehensive Cancer Network

JF - Journal of the National Comprehensive Cancer Network

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M1 - e250032

ER -

Adult Cancer Pain, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology

Abstract

Keywords

UN SDGs

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