A TCR mimic CAR T cell specific for NDC80 is broadly reactive with solid tumors and hematologic malignancies

Martin G. Klatt, Tao Dao, Zhiyuan Yang, Jianying Liu, Sung Soo Mun, Megan M. Dacek, Hanzhi Luo, Thomas J. Gardner, Christopher Bourne, Leila Peraro, Zita E. H. Aretz, Tanya Korontsvit, Michael Lau, Michael G. Kharas, Cheng Liu, David A. Scheinberg

Research output: Contribution to journalArticlepeer-review

15 Scopus citations
Original languageEnglish
Pages (from-to)861-874
Number of pages14
JournalBlood
Volume140
Issue number8
DOIs
StatePublished - Aug 25 2022
Externally publishedYes

Keywords

  • Animals
  • Antibodies/metabolism
  • Cytoskeletal Proteins/metabolism
  • HLA-A Antigens
  • Hematologic Neoplasms/metabolism
  • Humans
  • Immunotherapy, Adoptive/methods
  • Mice
  • Neoplasms
  • Receptors, Antigen, T-Cell
  • T-Lymphocytes

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