A microdissection library of the rat renal carcinoma gene region

D. W. Bell; R. S. Yeung; S. K. Bohlander; J. Q. Cheng; F. Jin; Joseph R. Testa

doi:10.1159/000133999

A microdissection library of the rat renal carcinoma gene region

D. W. Bell
, R. S. Yeung
, S. K. Bohlander
, J. Q. Cheng
, F. Jin
, Joseph R. Testa

Cancer Prevention and Control (CPC)

Fox Chase Cancer Center
University of Chicago

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Predisposition to hereditary renal carcinoma in the Eker rat involves a mutation of a putative tumor suppressor gene within chromosome band 10q12. We describe the identification of three unique polymorphic sequences in the vicinity of this locus following the microdissection, construction and characterization of a region-specific DNA library for rat chromosome band 10ql2.

Original language	English
Pages (from-to)	92-94
Number of pages	3
Journal	Cytogenetics and Cell Genetics
Volume	70
Issue number	1-2
DOIs	https://doi.org/10.1159/000133999
State	Published - 1995

Keywords

Animals
Blotting, Southern
Carcinoma, Renal Cell/genetics
Chromosome Mapping
Dissection/methods
Gene Library
In Situ Hybridization, Fluorescence
Kidney Neoplasms/genetics
Micromanipulation
Polymerase Chain Reaction
Rats

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10.1159/000133999

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title = "A microdissection library of the rat renal carcinoma gene region",

abstract = "Predisposition to hereditary renal carcinoma in the Eker rat involves a mutation of a putative tumor suppressor gene within chromosome band 10q12. We describe the identification of three unique polymorphic sequences in the vicinity of this locus following the microdissection, construction and characterization of a region-specific DNA library for rat chromosome band 10ql2.",

keywords = "Animals, Blotting, Southern, Carcinoma, Renal Cell/genetics, Chromosome Mapping, Dissection/methods, Gene Library, In Situ Hybridization, Fluorescence, Kidney Neoplasms/genetics, Micromanipulation, Polymerase Chain Reaction, Rats",

author = "Bell, \{D. W.\} and Yeung, \{R. S.\} and Bohlander, \{S. K.\} and Cheng, \{J. Q.\} and F. Jin and Testa, \{Joseph R.\}",

year = "1995",

doi = "10.1159/000133999",

language = "English",

volume = "70",

pages = "92--94",

journal = "Cytogenetics and Cell Genetics",

issn = "0301-0171",

publisher = "S. Karger AG",

number = "1-2",

}

TY - JOUR

T1 - A microdissection library of the rat renal carcinoma gene region

AU - Bell, D. W.

AU - Yeung, R. S.

AU - Bohlander, S. K.

AU - Cheng, J. Q.

AU - Jin, F.

AU - Testa, Joseph R.

PY - 1995

Y1 - 1995

N2 - Predisposition to hereditary renal carcinoma in the Eker rat involves a mutation of a putative tumor suppressor gene within chromosome band 10q12. We describe the identification of three unique polymorphic sequences in the vicinity of this locus following the microdissection, construction and characterization of a region-specific DNA library for rat chromosome band 10ql2.

AB - Predisposition to hereditary renal carcinoma in the Eker rat involves a mutation of a putative tumor suppressor gene within chromosome band 10q12. We describe the identification of three unique polymorphic sequences in the vicinity of this locus following the microdissection, construction and characterization of a region-specific DNA library for rat chromosome band 10ql2.

KW - Animals

KW - Blotting, Southern

KW - Carcinoma, Renal Cell/genetics

KW - Chromosome Mapping

KW - Dissection/methods

KW - Gene Library

KW - In Situ Hybridization, Fluorescence

KW - Kidney Neoplasms/genetics

KW - Micromanipulation

KW - Polymerase Chain Reaction

KW - Rats

UR - https://www.scopus.com/pages/publications/0028969208

U2 - 10.1159/000133999

DO - 10.1159/000133999

M3 - Article

C2 - 7736798

AN - SCOPUS:0028969208

SN - 0301-0171

VL - 70

SP - 92

EP - 94

JO - Cytogenetics and Cell Genetics

JF - Cytogenetics and Cell Genetics

IS - 1-2

ER -

A microdissection library of the rat renal carcinoma gene region

Abstract

Keywords

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