A microdissection library of the rat renal carcinoma gene region

D. W. Bell; R. S. Yeung; S. K. Bohlander; J. Q. Cheng; F. Jin; Joseph R. Testa

doi:10.1159/000133999

A microdissection library of the rat renal carcinoma gene region

D. W. Bell, R. S. Yeung, S. K. Bohlander, J. Q. Cheng, F. Jin, Joseph R. Testa

Cancer Prevention and Control (CPC)

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Predisposition to hereditary renal carcinoma in the Eker rat involves a mutation of a putative tumor suppressor gene within chromosome band 10q12. We describe the identification of three unique polymorphic sequences in the vicinity of this locus following the microdissection, construction and characterization of a region-specific DNA library for rat chromosome band 10ql2.

Original language	English
Pages (from-to)	92-94
Number of pages	3
Journal	Cytogenetics and Cell Genetics
Volume	70
Issue number	1-2
DOIs	https://doi.org/10.1159/000133999
State	Published - 1995

Keywords

Animals
Blotting, Southern
Carcinoma, Renal Cell/genetics
Chromosome Mapping
Dissection/methods
Gene Library
In Situ Hybridization, Fluorescence
Kidney Neoplasms/genetics
Micromanipulation
Polymerase Chain Reaction
Rats

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10.1159/000133999

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title = "A microdissection library of the rat renal carcinoma gene region",

abstract = "Predisposition to hereditary renal carcinoma in the Eker rat involves a mutation of a putative tumor suppressor gene within chromosome band 10q12. We describe the identification of three unique polymorphic sequences in the vicinity of this locus following the microdissection, construction and characterization of a region-specific DNA library for rat chromosome band 10ql2.",

keywords = "Animals, Blotting, Southern, Carcinoma, Renal Cell/genetics, Chromosome Mapping, Dissection/methods, Gene Library, In Situ Hybridization, Fluorescence, Kidney Neoplasms/genetics, Micromanipulation, Polymerase Chain Reaction, Rats",

author = "Bell, {D. W.} and Yeung, {R. S.} and Bohlander, {S. K.} and Cheng, {J. Q.} and F. Jin and Testa, {Joseph R.}",

year = "1995",

doi = "10.1159/000133999",

language = "English",

volume = "70",

pages = "92--94",

journal = "Cytogenetics and Cell Genetics",

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publisher = "S. Karger AG",

number = "1-2",

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TY - JOUR

T1 - A microdissection library of the rat renal carcinoma gene region

AU - Bell, D. W.

AU - Yeung, R. S.

AU - Bohlander, S. K.

AU - Cheng, J. Q.

AU - Jin, F.

AU - Testa, Joseph R.

PY - 1995

Y1 - 1995

N2 - Predisposition to hereditary renal carcinoma in the Eker rat involves a mutation of a putative tumor suppressor gene within chromosome band 10q12. We describe the identification of three unique polymorphic sequences in the vicinity of this locus following the microdissection, construction and characterization of a region-specific DNA library for rat chromosome band 10ql2.

AB - Predisposition to hereditary renal carcinoma in the Eker rat involves a mutation of a putative tumor suppressor gene within chromosome band 10q12. We describe the identification of three unique polymorphic sequences in the vicinity of this locus following the microdissection, construction and characterization of a region-specific DNA library for rat chromosome band 10ql2.

KW - Animals

KW - Blotting, Southern

KW - Carcinoma, Renal Cell/genetics

KW - Chromosome Mapping

KW - Dissection/methods

KW - Gene Library

KW - In Situ Hybridization, Fluorescence

KW - Kidney Neoplasms/genetics

KW - Micromanipulation

KW - Polymerase Chain Reaction

KW - Rats

UR - http://www.scopus.com/inward/record.url?scp=0028969208&partnerID=8YFLogxK

U2 - 10.1159/000133999

DO - 10.1159/000133999

M3 - Article

C2 - 7736798

AN - SCOPUS:0028969208

SN - 0301-0171

VL - 70

SP - 92

EP - 94

JO - Cytogenetics and Cell Genetics

JF - Cytogenetics and Cell Genetics

IS - 1-2

ER -

A microdissection library of the rat renal carcinoma gene region

Abstract

Keywords

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