A 25 year perspective on the evolution and advances in an understanding of the biology, evaluation and treatment of kidney cancer

Daniel M. Geynisman; Jodi K. Maranchie; Mark W. Ball; Gennady Bratslavsky; Eric A. Singer

doi:10.1016/j.urolonc.2021.04.038

A 25 year perspective on the evolution and advances in an understanding of the biology, evaluation and treatment of kidney cancer

Daniel M. Geynisman
, Jodi K. Maranchie
, Mark W. Ball
, Gennady Bratslavsky
, Eric A. Singer

University of Pittsburgh
National Institutes of Health
SUNY Upstate Medical University
Rutgers - The State University of New Jersey, New Brunswick

Research output: Contribution to journal › Review article › peer-review

15 Scopus citations

Abstract

The diagnosis, evaluation and management of patients with renal cell carcinoma has transformed in the 21st century. Utilizing biological discoveries and technological advances, the field has moved from blunt surgical and largely ineffective medical treatments, to nuanced and fine-tuned approaches based on biology, extent of disease and patient preferences. In this review we will summarize the last 25 years of progress in kidney cancer.

Original language	English
Pages (from-to)	548-560
Number of pages	13
Journal	Urologic Oncology: Seminars and Original Investigations
Volume	39
Issue number	9
DOIs	https://doi.org/10.1016/j.urolonc.2021.04.038
State	Published - Sep 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Kidney cancer
Molecular biology
Nephrectomy
Renal cell carcinoma
Systemic therapy

Access to Document

10.1016/j.urolonc.2021.04.038

Cite this

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title = "A 25 year perspective on the evolution and advances in an understanding of the biology, evaluation and treatment of kidney cancer",

abstract = "The diagnosis, evaluation and management of patients with renal cell carcinoma has transformed in the 21st century. Utilizing biological discoveries and technological advances, the field has moved from blunt surgical and largely ineffective medical treatments, to nuanced and fine-tuned approaches based on biology, extent of disease and patient preferences. In this review we will summarize the last 25 years of progress in kidney cancer.",

keywords = "Kidney cancer, Molecular biology, Nephrectomy, Renal cell carcinoma, Systemic therapy",

author = "Geynisman, \{Daniel M.\} and Maranchie, \{Jodi K.\} and Ball, \{Mark W.\} and Gennady Bratslavsky and Singer, \{Eric A.\}",

note = "Publisher Copyright: {\textcopyright} 2021 Elsevier Inc.",

year = "2021",

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language = "English",

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T1 - A 25 year perspective on the evolution and advances in an understanding of the biology, evaluation and treatment of kidney cancer

AU - Geynisman, Daniel M.

AU - Maranchie, Jodi K.

AU - Ball, Mark W.

AU - Bratslavsky, Gennady

AU - Singer, Eric A.

PY - 2021/9

Y1 - 2021/9

N2 - The diagnosis, evaluation and management of patients with renal cell carcinoma has transformed in the 21st century. Utilizing biological discoveries and technological advances, the field has moved from blunt surgical and largely ineffective medical treatments, to nuanced and fine-tuned approaches based on biology, extent of disease and patient preferences. In this review we will summarize the last 25 years of progress in kidney cancer.

AB - The diagnosis, evaluation and management of patients with renal cell carcinoma has transformed in the 21st century. Utilizing biological discoveries and technological advances, the field has moved from blunt surgical and largely ineffective medical treatments, to nuanced and fine-tuned approaches based on biology, extent of disease and patient preferences. In this review we will summarize the last 25 years of progress in kidney cancer.

KW - Kidney cancer

KW - Molecular biology

KW - Nephrectomy

KW - Renal cell carcinoma

KW - Systemic therapy

UR - https://www.scopus.com/pages/publications/85108193164

U2 - 10.1016/j.urolonc.2021.04.038

DO - 10.1016/j.urolonc.2021.04.038

M3 - Review article

C2 - 34092483

SN - 1078-1439

VL - 39

SP - 548

EP - 560

JO - Urologic Oncology: Seminars and Original Investigations

JF - Urologic Oncology: Seminars and Original Investigations

IS - 9

ER -

A 25 year perspective on the evolution and advances in an understanding of the biology, evaluation and treatment of kidney cancer

Abstract

UN SDGs

Keywords

Access to Document

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