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2025
20 years of histone lysine demethylases: From discovery to the clinic and beyond
Gray, Z. H., Honer, M. A., Ghatalia, P., Shi, Y. & Whetstine, J. R., Apr 3 2025, In: Cell. 188, 7, p. 1747-1783 37 p.Research output: Contribution to journal › Review article › peer-review
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A case report with pathological insights into cotyledonoid dissecting leiomyoma: Essential for differentiating this rare benign tumor from cancer
Edalati, M., Khouri, K., Lazim, A., Wei, S., Seth, A. & Proca, D., Jun 2025, In: Case Reports in Women's Health. 46, p. e00719 e00719.Research output: Contribution to journal › Article › peer-review
Open Access -
A comparison of isolated limb infusion/perfusion, immune checkpoint inhibitors, and intralesional therapy as first-line treatment for patients with melanoma in-transit metastases
DePalo, D. K., Dugan, M. M., Naqvi, S. M. H., Ollila, D. W., Hieken, T. J., Block, M. S., van Houdt, W. J., Wouters, M. W. J. M., Reijers, S. J. M., Asher, N., Broman, K. K., Duncan, Z., Anderson, M., Gyorki, D. E., Snow, H., Held, J., Farma, J. M., Vetto, J. T., Hui, J. Y. C. & Kolbow, M. & 10 others, , Jan 1 2025, In: Cancer. 131, 1, p. e35636 e35636.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
A Cross-Sectional Analysis of Psychosocial Mediators Between Discrimination and Health-Related Quality of Life Among Sexual and Gender Minority Cancer Survivors
Franco-Rocha, O. Y., Wheldon, C. W., Phillips, C. S., Patel, M., Whittaker, T. A., Kesler, S. R. & Henneghan, A. M., Apr 2025, In: Psycho-Oncology. 34, 4, e70154.Research output: Contribution to journal › Article › peer-review
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Adapting and applying intervention mapping to integrate medical-legal partnership into organizations providing HIV care: an implementation methodology study
Muñoz-Laboy, M., French, A., Davison, R., Morton, S. J., Arnold, E. A., Rudolph, A. E., Jones, R. M., Fernandez, M. I. & Martinez, O., 2025, In: Frontiers in Health Services. 5, p. 1435663 1435663.Research output: Contribution to journal › Article › peer-review
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A Difficult Conversation
Geynisman, D. M., Apr 2025, In: JNCCN Journal of the National Comprehensive Cancer Network. 23, 4, e250019.Research output: Contribution to journal › Editorial
Open Access -
A Digital Intervention to Address Sexual Health in Hematopoietic Stem Cell Transplant Survivors
El-Jawahri, A., Reese, J. B., Traeger, L., Dizon, D., Cutler, C., Bober, S., Greer, J. A., Vanderklish, J., Rabideau, D. J., Cronin, K., Reynolds, M., Ufere, N., Rice, J., Clay, M., Newcomb, R., DeFilipp, Z., Ho, V., Soiffer, R. J., Pensak, N. & Yi-Bin, C. & 1 others, , Feb 2025, In: JNCCN Journal of the National Comprehensive Cancer Network. 23, 2, e247076.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Adjuvant Pembrolizumab versus Observation in Muscle-Invasive Urothelial Carcinoma
Apolo, A. B., Ballman, K. V., Sonpavde, G., Berg, S., Kim, W. Y., Parikh, R., Teo, M. Y., Sweis, R. F., Geynisman, D. M., Grivas, P., Chatta, G., Reichert, Z. R., Kim, J. W., Bilen, M. A., McGregor, B., Singh, P., Tripathi, A., Cole, S., Simon, N. & Niglio, S. & 20 others, , Jan 2 2025, In: New England Journal of Medicine. 392, 1, p. 45-55 11 p.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
Adrenal Surgery: Open, Laparoscopic, and Robotic Approaches
Sholklapper, T., Omil-Lima, D. & Kutikov, A., May 2025, In: Urologic Clinics of North America. 52, 2, p. 261-273 13 p.Research output: Contribution to journal › Review article › peer-review
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Advance care planning discussions - Perspectives from oncology patients with advanced-stage disease
Pendleton, D., Egleston, B. L. & Fang, C. Y., Apr 7 2025, In: Palliative and Supportive Care. 23, p. e90 e90.Research output: Contribution to journal › Article › peer-review
Open Access -
Afatinib and Necitumumab in EGFR-Mutant NSCLC with Acquired Resistance to Tyrosine Kinase Inhibitors
Myall, N. J., Whisenant, J. G., Neal, J. W., Iams, W. T., Reckamp, K. L., York, S., Berry, L. D., Shyr, Y., Horn, L., Wakelee, H. A. & Padda, S. K., Feb 2025, In: JTO Clinical and Research Reports. 6, 2, p. 100757 100757.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Age-Associated Activation of the cGAS-STING Pathway and Impairment of DNA Damage Repair in Human Primary Alveolar Type II Cells
Lin, C.-R., Hayek, H., Simborio, H., Karim, L., Bahmed, K., Bolla, S., Marchetti, N., Criner, G. J., Tian, Y. & Kosmider, B., Jan 24 2025, (E-pub ahead of print) In: Aging and Disease.Research output: Contribution to journal › Article › peer-review
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Age at first full-term pregnancy and other reproductive factors are associated with mammographic breast density in postmenopausal women: a study in Flanders, Belgium
Vandeloo, M. J., Kellen, E., Fang, C. Y., Ross, E. A., Vancoillie, L., Bruckers, L. M., Neven, K. Y., Bijnens, E. M., Nawrot, T. S. & Van Ongeval, C., Feb 1 2025, In: Cancer Research Communications. 5, 2, p. 267-276 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A Geospatial Analysis of the Lung Cancer Burden in Philadelphia, Using Pennsylvania Cancer Registry Data from 2008–2017
McIntire, R. K., Senter, K., Shusted, C., Yearwood, R., Barta, J., Keith, S. W. & Zeigler-Johnson, C., Mar 20 2025, In: International Journal of Environmental Research and Public Health. 22, 3, 455.Research output: Contribution to journal › Article › peer-review
Open Access -
A guide for transition from cardiothoracic surgery training to practice
Hameed, I., Talapaneni, S., Barron, L. M., Lin, Y., Mitzman, B., Okusanya, O. T., Woodard, G. A., Louis, C., Al Rameni, D., Mehaffey, J. H., Freeman, K. A., Lou, X., Dhanasopon, A. P., Pereira, S., Erkmen, C. & Svensson, L. G., Apr 1 2025, (E-pub ahead of print) In: Journal of Thoracic and Cardiovascular Surgery.Research output: Contribution to journal › Editorial
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Alzheimer's disease as an auto-innate immune pathology with potential cell trans-differentiation and enhanced trained immunity in 3xTg-AD mouse model
Saaoud, F., Liu, L., Xu, K., Lu, Y., Shao, Y., Ben Issa, M., Jiang, X., Wang, X., Liu, X., Autieri, M., Wu, S., Wei, J., Yu, J., Bouchareb, R., Gillespie, A., Luo, J. J., Martinez, L., Vazquez-Padron, R., Sun, J. & Zhao, H. & 3 others, , May 2025, In: Journal of Alzheimer's Disease. 105, 2, p. 550-572 23 p.Research output: Contribution to journal › Article › peer-review
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A macrophage-neutrophil program drives mammary carcinogenesis
Bolini, L., Knott, S. R. V. & Galluzzi, L., May 2025, In: Trends in Cancer. 11, 5, p. 427-429 3 p.Research output: Contribution to journal › Article › peer-review
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American Radium Society™ Appropriate Use Criteria Systematic Review and Guidelines on Reirradiation for Non-small Cell Lung Cancer Executive Summary
Simone, C. B., Amini, A., Chetty, I. J., Choi, J. I., Chun, S. G., Donington, J., Edelman, M. J., Higgins, K. A., Kestin, L. L., Mohindra, P., Movsas, B., Rodrigues, G. B., Rosenzweig, K. E., Rybkin, I. I., Shepherd, A. F., Slotman, B. J., Wolf, A. & Chang, J. Y., Apr 2 2025, (E-pub ahead of print) In: International Journal of Radiation Oncology Biology Physics.Research output: Contribution to journal › Review article › peer-review
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A multicenter evaluation of penile curvature correction in men with Peyronie's disease undergoing inflatable penile prosthesis placement
Hammad, M. A. M., Barham, D. W., Simhan, J., Nguyen, T., Swerdloff, D., Miller, J., Hatzichristodoulou, G., Sempels, M., Andrianne, R., Hotaling, J. M., Hsieh, T.-C., Jones, J. M., Modgil, V., Osmonov, D., Pearce, I., Perito, P., Sadeghi-Nejad, H., Suarez-Sarmiento, A., Yafi, F. A. & Gross, M. S., Feb 1 2025, In: Journal of Sexual Medicine. 22, 2, p. 349-355 7 p., qdae192.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
A New Administration and JNCCN
Geynisman, D. M., Mar 2025, In: Journal of the National Comprehensive Cancer Network. 23, 3, p. 65-65 1 p.Research output: Contribution to journal › Editorial
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An Imperative to Include Children's Voices in Policy Development: Part of the Solution to Understanding the Impact of Policy on Children's Mental Health
International Network for Epidemiology in Policy (INEP), Jan 2025, In: Journal of the American Academy of Child and Adolescent Psychiatry. 64, 1, p. 3-4 2 p.Research output: Contribution to journal › Letter › peer-review
1 Scopus citations -
An International Delphi Consensus About Tumor Rupture During Robotic Partial Nephrectomy (Researching UnPredictable TUmor RupturE during Robotic Partial Nephrectomy—The RUPTURE Project)
Bertolo, R., Antonelli, A., Bex, A., Anderson, C., Autorino, R., Barber, N., Badani, K., Barod, R., Bensalah, K., Bernhard, J. C., Breda, A., Capitanio, U., Challacombe, B., Crivellaro, S., De Groote, R., Derweesh, I., Galfano, A., Harke, N., Kaouk, J. & Kutikov, A. & 17 others, , 2025, (Accepted/In press) In: European Urology Open Science.Research output: Contribution to journal › Article › peer-review
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A novel pharmacological entity toward integrated multimodal immunotherapy
Sirera, R., Beltrán-Visiedo, M. & Galluzzi, L., Feb 2025, In: Trends in Pharmacological Sciences. 46, 2, p. 95-97 3 p.Research output: Contribution to journal › Article › peer-review
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A Phase 2 Single-Arm Trial of High-Dose Precision Targeted Radiation Therapy Added to Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer
Gensheimer, M. F., Kotha, N. V., Vitzthum, L. K., Chin, A. L., Jackson, S., 't Erve, I. V., Pratapneni, A., Le-Budka, M.-L., Wong, S., Brown, E., Barnick, K., Wakelee, H. A., Das, M., Ramchandran, K. J., Myall, N. J., Padda, S., Marquez, C. M., Million, L., Chen, T. T. & Man, M. C. & 8 others, , Mar 1 2025, In: International Journal of Radiation Oncology Biology Physics. 121, 3, p. 711-719 9 p.Research output: Contribution to journal › Article › peer-review
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A phase 2 study of decitabine with or without carboplatin and arsenic trioxide in patients with MDS and AML
Kropf, P. L., Chung, W., Shameem, R., Xiao, L., Balch, C., Huang, X. & Issa, J.-P. J., May 2025, In: Blood neoplasia. 2, 2, p. 100071Research output: Contribution to journal › Article › peer-review
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A phase I, first-in-human trial of KO-947, an ERK1/2 inhibitor, in patients with advanced solid tumors
Schram, A. M., Boni, V., Adjei, A. A., Olszanski, A. J., Vieito, M., Francis, J. H., Kurman, M., Ahsan, J. M., Tomkinson, B. & Garralda, E., Mar 2025, In: ESMO Open. 10, 3, p. 104300 104300.Research output: Contribution to journal › Article › peer-review
Open Access -
A Practical Guide for the Management of Toxicities Associated with Belzutifan
Li, J. & Ghatalia, P., Apr 22 2025, (E-pub ahead of print) In: European Urology Focus.Research output: Contribution to journal › Article › peer-review
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A pretreatment nomogram to predict muscle-invasiveness in high-risk upper tract urothelial carcinoma (ROBUUST 2.0 collaborative group)
Ditonno, F., Franco, A., Bologna, E., Veccia, A., Bertolo, R., Wang, L., Abdollah, F., Finati, M., Simone, G., Tuderti, G., Helstrom, E., Correa, A., de Cobelli, O., Ferro, M., Porpiglia, F., Amparore, D., Checcucci, E., Tufano, A., Perdonà, S. & Bhanvadia, R. & 19 others, , Feb 2025, In: Minerva Urology and Nephrology. 77, 1, p. 57-68 12 p.Research output: Contribution to journal › Article › peer-review
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A Proposed mHealth Intervention to Address Patient Barriers to Colposcopy Attendance: Qualitative Interview Study of Clinic Staff and Patient Perspectives
Hemler, J. R., Wagner, R. B., Sullivan, B., Macenat, M., Tagai, E. K., Vega, J., Hernandez, E., Miller, S. M., Wen, K.-Y., Ayers, C., Einstein, M. H., Hudson, S. V. & Kohler, R. E., Jan 14 2025, In: JMIR Formative Research. 9, p. e55043 e55043.Research output: Contribution to journal › Article › peer-review
Open Access -
A Randomized, Controlled Trial Evaluating Perioperative Risk-stratification and Risk-based, Protocol-driven Management After Elective Major Cancer Surgery
Esnaola, N. F., Chelluri, R., Castellanos, J., Altman, A., Chen, D. Y. T., Chu, C., Farma, J. M., Haber, A., Sheriff, F., Huang, C., Kutikov, A., Patel, S., Patrick, K., Reddy, S., Rubin, S., Viterbo, R., Ridge, J. A., Edelman, M., Ross, E. & Smaldone, M. & 1 others, , Mar 2025, In: Annals of Surgery. 281, 3, p. 395-403 9 p.Research output: Contribution to journal › Article › peer-review
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Are all programmed cell death protein 1 inhibitors the same?
Lorch, J. H., Stein, S. & Edelman, M. J., 2025, In: Frontiers in Oncology. 15, p. 1535030 1535030.Research output: Contribution to journal › Review article › peer-review
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A reproducibility study on invasion in small pulmonary adenocarcinoma according to the WHO and a modified classification, supported by biomarkers
Thunnissen, E., Blaauwgeers, H., Filipello, F., Lissenberg-Witte, B., Minami, Y., Noguchi, M., Quesne, J. L., Papotti, M. G., Flieder, D. B., Pelosi, G., Sansano, I., Berezowska, S., Ryška, A., Brcic, L., Motoi, N., Nakatani, Y., Kuempers, C., Hofman, P., Hofman, V. & Dale, V. G. & 34 others, , Jan 2025, In: Lung Cancer. 199, p. 108060 108060.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
A retinoic acid:YAP1 signaling axis controls atrial lineage commitment
Abraham, E., Kostina, A., Volmert, B., Roule, T., Huang, L., Yu, J., Williams, A. E., Megill, E., Douglas, A., Pericak, O. M., Morris, A., Stronati, E., Larrinaga-Zamanillo, A., Fueyo, R., Zubillaga, M., Andrake, M. D., Akizu, N., Aguirre, A. & Estaras, C., May 27 2025, In: Cell Reports. 44, 5, p. 115687 115687.Research output: Contribution to journal › Article › peer-review
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Arterial Stiffness, Central Blood Pressure, and the Risk of Incident Stroke in Hypertensive Adults
Cao, T., Cheng, Z., Wei, Y., Ding, C., Lu, W. Y., Gao, L., Liu, L., Zhang, Y., Li, J., Huo, Y., Spence, J. D., Wang, X., Cheng, X., Wang, H. & Huang, X., May 2025, In: European Journal of Neurology. 32, 5, p. e70178 e70178.Research output: Contribution to journal › Article › peer-review
Open Access -
Artificial Intelligence Augmentation: Performance of GPT-4 and GPT-3.5 on the Plastic Surgery In-service Examination
Najafali, D., Reiche, E., Araya, S., Orellana, M., Liu, F. C., Camacho, J. M., Patel, S. A., Broyles, J. M., Dorafshar, A. H., Morrison, S. D., Knoedler, L. & Fox, P. M., Apr 25 2025, In: Plastic and Reconstructive Surgery - Global Open. 13, 4, p. e6645Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models
Ren, F., Aliper, A., Chen, J., Zhao, H., Rao, S., Kuppe, C., Ozerov, I. V., Zhang, M., Witte, K., Kruse, C., Aladinskiy, V., Ivanenkov, Y., Polykovskiy, D., Fu, Y., Babin, E., Qiao, J., Liang, X., Mou, Z., Wang, H. & Pun, F. W. & 10 others, , Jan 2025, In: Nature Biotechnology. 43, 1, p. 63-75 13 p., 13427.Research output: Contribution to journal › Article › peer-review
Open Access91 Scopus citations -
ASO Author Reflections: Beyond the Binary: Using IHC Status to Predict Response to Neoadjuvant Therapy in HER2+ Early-Stage Breast Cancer
Winer, L. K. & Williams, A. D., Feb 2025, In: Annals of Surgical Oncology. 32, 2, p. 967-968 2 p.Research output: Contribution to journal › Article › peer-review
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ASO Author Reflections: Removing the Element of Surprise: Reducing Unplanned Excisions to Enhance Dermatofibrosarcoma Protuberans Outcomes
Winer, L. K., Farma, J. M. & Villano, A. M., Jul 2025, In: Annals of Surgical Oncology. 32, 7, p. 5367-5368 2 p.Research output: Contribution to journal › Article › peer-review
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ASO Visual Abstract: Immunohistochemical Status Predicts Pathologic Complete Response to Neoadjuvant Therapy in HER2 Overexpressing Breast Cancers
Winer, L., Ruth, K. J., Bleicher, R. J., Nagarathinam, R., Mcshane, M., Porpiglia, A. S., Pronovost, M. T., Aggon, A. & Williams, A. D., Jan 2025, In: Annals of Surgical Oncology. 32, p. 979-980 2 p.Research output: Contribution to journal › Article › peer-review
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ASO Visual Abstract: Commission on Cancer Center Performance with the New Breast Cancer Quality Measures: A Review of Historical Data
Fefferman, M. L., Thompson, D. M., Wilke, L. G., Hwang, S., Bleicher, R., Freedman, L. M., Meisel, J. L., Kuchta, K. & Yao, K., Mar 1 2025, In: Annals of Surgical Oncology. 32, 3, p. 2112-2113 2 p.Research output: Contribution to journal › Article › peer-review
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ASO Visual Abstract: Low Socioeconomic Status at the Patient and Institutional Level Impact Achievement of Breast Cancer Quality Standards
HoSang, K. M., Bleicher, R. J., Yao, K. A., Dietz, J. R. & Williams, A. D., Jun 29 2025, (E-pub ahead of print) In: Annals of Surgical Oncology.Research output: Contribution to journal › Article › peer-review
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ASO Visual Abstract: Examining the Impact of Biopsy Technique on Clinical and Pathologic Outcomes in Dermatofibrosarcoma Protuberans-An International, Multi-Institutional Study
Winer, L. K., Fredette, J. D., Hasler, J., Akumuo, R., Greco, S. H., von Mehren, M., Bartholomew, A. J., Blazer, D. G., Gabrielova, L., Adamkova, D., Bernard-Bedard, E., Nessim, C., Kollar, A., Olariu, R., Cencelj-Arnez, R., Hompes, D., Ford, S. J., Cardona, K., Sato, K. & Iwata, S. & 2 others, , Mar 24 2025, In: Annals of Surgical Oncology. 2 p.Research output: Contribution to journal › Article › peer-review
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Assessing residential neighborhood exposomes and their associations with cancer incidence: rationale, study design, and methods
Jones, R. M., Han, I., Hughes, J. & Nelson, E. J., May 2 2025, (E-pub ahead of print) In: American Journal of Epidemiology.Research output: Contribution to journal › Article › peer-review
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Association between antibiotics and treatment efficacy in metastatic urothelial carcinoma patients
Braun, A., Deng, M., Hasler, J. S., Bukavina, L., Handorf, E. & Abbosh, P. H., Feb 25 2025, In: BMC Medicine. 23, 1, p. 117 117.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Association between Locoregional Failure and NFE2L2/KEAP1/CUL3 Mutations in NRG/RTOG 9512: A Randomized Trial of Radiation Fractionation in T2N0 Glottic Cancer
Guan, L., Torres-Saavedra, P. A., Zhao, X., Major, M. B., Holmes, B. J., Nguyen, N. K., Kumaravelu, P., Hodge, T., Diehn, M., Zevallos, J. P., Holsinger, F. C., Emami, B., Jordan, R. C., Hayward, M. C., Sagar, S. M., Morrison, W., Schultz, C., Caudell, J. J., Jones, C. U. & Bratman, S. V. & 8 others, , May 1 2025, In: Clinical Cancer Research. 31, 9, p. 1615-1624 10 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Associations Between Sexual Script Flexibility and Sexual Outcomes: An Investigation Among Breast Cancer Survivor Couples
Reese, J. B., Sorice, K. A., Porter, L. S., Lepore, S. J., Langer, S. L., Hasler, J. & Pukall, C. F., Apr 2025, In: Psycho-Oncology. 34, 4, p. e70147 e70147.Research output: Contribution to journal › Article › peer-review
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A Structural Mechanism for Noncanonical GPCR Signal Transduction in the Hedgehog Pathway
Steiner, W. P., Iverson, N., Venkatakrishnan, V., Wu, J., Stepniewski, T. M., Michaelson, Z., Bröckel, J. W., Zhu, J.-F., Bruystens, J., Lee, A., Nelson, I., Bertinetti, D., Arveseth, C. D., Tan, G., Spaltenstein, P., Xu, J., Hüttenhain, R., Kay, M., Herberg, F. W. & Selent, J. & 4 others, , May 27 2025, (bioRxiv : the preprint server for biology).Research output: Working paper › Preprint
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A Technology-Based Educational Intervention and Multiple Domains of Symptom Experience: Asian American Breast Cancer Survivors
Im, E. O., Chee, W., Paul, S., Kim, S. Y., Choi, M. Y., Deatrick, J., Inouye, J., Ma, G., Mao, J., Meghani, S., Nguyen, G. T., Schapira, M., Ulrich, C., Yeo, S. A., Bao, T. & Shin, D., May 15 2025, (E-pub ahead of print) In: Journal of Cancer Education.Research output: Contribution to journal › Article › peer-review
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ATR promotes mTORC1 activity via de novo cholesterol synthesis
Tangudu, N. K., Grumet, A. N., Fang, R., Buj, R., Cole, A. R., Uboveja, A., Amalric, A., Yang, B., Huang, Z., Happe, C., Sun, M., Gelhaus, S. L., MacDonald, M. L., Hempel, N., Snyder, N. W., Kedziora, K. M., Valvezan, A. J. & Aird, K. M., Jun 13 2025, (E-pub ahead of print) In: EMBO Reports.Research output: Contribution to journal › Article › peer-review
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Author Correction: ChromaFold predicts the 3D contact map from single-cell chromatin accessibility (Nature Communications, (2024), 15, 1, (9432), 10.1038/s41467-024-53628-0)
Gao, V. R., Yang, R., Das, A., Luo, R., Luo, H., McNally, D. R., Karagiannidis, I., Rivas, M. A., Wang, Z. M., Barisic, D., Karbalayghareh, A., Wong, W., Zhan, Y. A., Chin, C. R., Noble, W. S., Bilmes, J. A., Apostolou, E., Kharas, M. G., Béguelin, W. & Viny, A. D. & 4 others, , Dec 2025, In: Nature Communications. 16, 1, 684.Research output: Contribution to journal › Comment/debate
Open Access