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Zachary A. Frosch

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Zachary A. Frosch, MD, MSHP

Assistant Professor

 https://orcid.org/0000-0002-4599-0533
20092026

Research activity per year

Personal profile

Personal profile

Treatment Philosophy

Receiving a cancer diagnosis and starting treatment can be overwhelming. Guiding patients through this difficult process is what first drew me to oncology. I work to help my patients understand their cancer and the different ways we can treat it. I also have a focus on teaching and education, which informs how I approach each conversation with my patients.

In addition to caring for patients, I conduct research in cancer care delivery, aiming to make the process of receiving cancer care simpler, faster, and more accessible to our patients.

Lab Overview

My research focuses on cancer care delivery. This work aims to make the process of receiving cancer care simpler, faster, and more accessible to patients. Recently, I have focused on two key areas: facilitating timely access to cancer treatment, and reducing disparities in the use of specialized therapies that are only available at certain cancer centers. My research is collaborative and draws on techniques from multiple disciplines. These include the analysis of cancer registry and electronic health record data, surveys, qualitative interviews, predictive analytics, and implementation science.

Treatment Focus

Hodgkin's and Non-Hodgkin's Lymphoma; Chronic Lymphocytic Leukemia

Research interests

  • Health services research
  • Cancer care delivery
  • Access to cancer treatment and cancer care disparities

URL

https://www.foxchase.org/zachary-frosch

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  • Hodgkin Lymphoma, Version 1.2026, NCCN Clinical Practice Guidelines In Oncology

    Advani, R. H., Kelsey, C. R., Armand, P., Bello, C. M., Benitez, C. M., Bond, D., Chen, W., Cherian, S., Czader, M., Dabaja, B., Daly, M. E., Frosch, Z., Gordon, L. I., Hansen, N., Herrera, A. F., Hochberg, E. P., Hoppe, R. T., Isufi, I., Johnston, P. B. & Kelly, K. & 18 others, Kenkre, V. P., Kline, J., Lynch, R. C., McConathy, J., Morgan, D., Niu, A., Paul, S., Rabinovitch, R., Salavati, A., Sano, D., Shah, H., Spinner, M., Svoboda, J., Winter, J. N., Yahalom, J., Yang, J. C., Montgomery, S. & Stehman, K., Feb 2026, In: JNCCN Journal of the National Comprehensive Cancer Network. 24, 2, p. 41-60 20 p.

    Research output: Contribution to journal › Article › peer-review

    6 Scopus citations

  • Prognosis and treatment of plasmablastic lymphoma in the United States: a multicenter retrospective study

    Hamby, M., Egleston, B. L., Frosch, Z. A. K., Steiner, R. E., Noy, A., Carvajal, V., Chong, E. R., Tolu, S. S., Jean-Louis, G., Amengual, J. E., Patel, R., Ahmed, S., Sharp, J., Voorhees, T., Baiocchi, R., Ramirez-Gamero, A., Castillo, J. J., Hamburger, E., Dittus, C. & Nizamuddin, I. A. & 27 others, Mehta-Shah, N., Thaw Dar, N. N., Sandoval-Sus, J., Rojek, A. E., Riedell, P. A., Khan, N., Danilov, A., Solipuram, V., Rubinstein, P. G., Ariotti, A., Suneja, G., Vartanov, A., Milrod, C., Olszewski, A. J., Smilnak, G., Ayers, E., Desai, S., Rhodes, J. M., Magarelli, G., Feldman, T., Pellon, M., Aboulafia, D. M., Bae, W., Galvez, C., Bhatlapenumarthi, V., Hamadani, M. & Barta, S. K., Mar 23 2026, In: Blood Cancer Journal. 16, 1, 43.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Scopus citations

  • The Role of Fatalism in Coping: Disparities in Psychological Distress Among Patients With Indolent Blood Cancers

    Sklarz, T., Hasler, J. S., Fang, C. Y. & Frosch, Z. A. K., Apr 2026, In: Cancer Medicine. 15, 4, p. e71819 e71819.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • "I Missed My Other Oncologist": Established Relationships as Barriers and Facilitators to Accessing CAR-T and Autologous Transplantation

    Frosch, Z. A. K., Meshack, C., Meeker, C., Varshavsky-Yanovsky, A., Khanal, R., Bromberg, M., Chandar, A., Quien, E., Carter, J., Nakhoda, S. K., Messmer, M., Montgomery, C., Incorvati, J. A., Ali, N. D., Styler, M. J. & Fang, C. Y., Dec 2025, In: Cancer Medicine. 14, 23, p. e71425 e71425.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Scopus citations

  • Loncastuximab in high-risk and heavily pretreated relapsed/refractory diffuse large B-cell lymphoma: a real-world analysis from 21 US centers

    Zelikson, V., Gurumurthi, A., Sawalha, Y., Annunzio, K., Saha, A., Dong, N., Qualls, D., Amoozgar, B., Kahl, B., Baird, J., Challa, P., Huntington, S. F., Santos, J., Bair, S., Narkhede, M., Li, S., Frosch, Z., Ho, C., Smith, S. D. & Winter, A. & 19 others, Landsburg, D., Furqan, F., Hamadani, M., Baird, K., Romancik, J., Alharthy, H., Law, J., Bojanini, L., Advani, R., Hu, B., Johnson, P. C., Grover, N. S., Merril, M., Crombie, J. L., Shafagati, N., Sterling, C., Nastoupil, L. J., Epperla, N. & Ayers, E. C., Mar 2025, In: Haematologica. 110, 3, p. 706-714 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    9 Scopus citations
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