Calculated based on number of publications stored in Pure and citations from Scopus
Calculated based on number of publications stored in Pure and citations from Scopus
Calculated based on number of publications stored in Pure and citations from Scopus
20122025

Research activity per year

Personal profile

Research interests

My research interests focus on advancing precision medicine by leveraging bioinformatics, data science and interdisciplinary collaboration. My work aims to bridge computational approaches with clinical insights to address the complexities of tumor heterogeneity, particularly through multi-omics integration and predictive modeling. 

Specifically, I focus on:

  1. Biomarker Discovery and Validation: Developing and validating molecular biomarkers that can reliably predict cancer onset, progression, and response to therapies.

  2. Understanding Cancer Heterogeneity: Utilizing single-cell and bulk omics data to elucidate the genetic and molecular diversity within tumors and across patient populations. 

  3. Integrative Data Approaches for Treatment Prediction: Employing machine learning and AI to integrate multi-omics and clinical data, building models that predict treatment efficacy and resistance mechanisms. 

We collaborate with researchers and clinicians to design studies, analyze data, and develop data-driven products. We work on a variety of projects, including:

  • Collaborate with researchers to perform in-depth genomics and clinical data analysis, offer support in preparing manuscripts and grant applications.
  • Partner with clinicians to design studies and analyze data, develop data-driven products, and validate hypotheses using real-world evidence gathered from diverse consortium organizations, such as labs, hospitals, and literature mining.
  • Provide insightful data science consultation to pharmaceutical and biotech companies on new drug development, leveraging both short-reads and long-reads sequencing data analysis, and utilizing structured and unstructured patient's data for clinical research.

Education/Academic qualification

PhD, Electrical Engineering and Computer Science, Washington State University Pullman

Sep 2007Jul 2012

Award Date: Jul 1 2012

Master, Electrical Engineering, Nanjing University

Sep 2004Jul 2007

Award Date: Jul 1 2007

Bachelor, Electrical Engineering, Nanjing University

Sep 2000Jul 2004

Award Date: Jul 1 2004

External positions

Senior Scientist, The Children's Hospital of Philadelphia

Aug 2019Jan 2023

Assistant Professor, University of Mississippi Medical Center

Jul 2016Jul 2019

Computational Biologist II, UT Southwestern Medical Center

Nov 2012Jul 2016

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