Personal profile
Research interests
Lab Overview
My Lab's core affiliation is with the Cancer Prevention and Control Program at FCCC. In addition, I hold an adjunct position in the Department of Radiation Oncology, am a member of the Cancer Epigenetics Institute within FCCC and maintain adjunct faculty roles at Drexel University School of Medicine, Temple University’s Lewis Katz School of Medicine, and its College of Public Health.
My principal focus revolves around understanding how innate genetic variation in DNA repair can shape an individual's predisposition to cancer and influence the outcomes for patients undergoing DNA-damaging treatments, such as chemotherapy and radiation. As a trained molecular geneticist, I delve into studying polymorphisms or mutations that may compromise the efficiency of DNA damage response and repair. With this knowledge, our goal is to identify biomarkers that can predict cancer susceptibility and treatment outcomes. These potential biomarkers include unique genes, their polymorphisms, proteins, and other molecular signifiers that shed light on both cancer risks and patient outcomes. In my lab, we adopt a multi-disciplinary approach, harnessing techniques from molecular genetics, biochemistry, and cellular biology. We actively collaborate with a diverse group of professionals, including clinicians, epidemiologists, bioinformaticians, and computational biologists.
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Collaborations and top research areas from the last five years
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Metabolic and proteomic signatures differentiate inflammatory phenotypes from cancer and predict treatment response in patient sera
Cutshaw, G., Demidova, E. V., Czyzewicz, P., Quam, E., Lorang, N., AL Siyabi, A. W., Batra, S., Arora, S. & Bardhan, R., Sep 2025, In: Bioengineering and Translational Medicine. 10, 5, p. e70029 e70029.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Erratum: Correction: Exploring Co-occurring POLE Exonuclease and Non-exonuclease Domain Mutations and Their Impact on Tumor Mutagenicity (Cancer research communications (2024))
Shah, S. M., Demidova, E. V., Ringenbach, S., Faezov, B., Andrake, M., Gandhi, A., Mur, P., Viana-Errasti, J., Xiu, J., Swensen, J., Valle, L., Dunbrack, R. L., Hall, M. J. & Arora, S., May 31 2024, In: Cancer Research Communications. 4, 5, p. 1398 1 p.Research output: Contribution to journal › Comment/debate
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Exploring Co-occurring POLE Exonuclease and Non-exonuclease Domain Mutations and Their Impact on Tumor Mutagenicity
Shah, S. M., Demidova, E. V., Ringenbach, S., Faezov, B., Andrake, M., Gandhi, A., Mur, P., Viana-Errasti, J., Xiu, J., Swensen, J., Valle, L., Dunbrack, R. L., Hall, M. J. & Arora, S., Jan 26 2024, In: Cancer Res Commun. 4, 1, p. 213-225 13 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Factors Associated With Racial and Ethnic Disparities in Locally Advanced Rectal Cancer Outcomes
Shulman, R. M., Deng, M., Handorf, E. A., Meyer, J. E., Lynch, S. M. & Arora, S., Feb 29 2024, In: Jama Network Open. 7, 2, p. e240044Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Author Correction: Polλ promotes microhomology-mediated end-joining (Nature Structural & Molecular Biology, (2023), 30, 1, (107-114), 10.1038/s41594-022-00895-4)
Chandramouly, G., Jamsen, J., Borisonnik, N., Tyagi, M., Calbert, M. L., Tredinnick, T., Ozdemir, A. Y., Kent, T., Demidova, E. V., Arora, S., Wilson, S. H. & Pomerantz, R. T., Jul 2023, In: Nature Structural and Molecular Biology. 30, 7, p. 1048 1 p.Research output: Contribution to journal › Comment/debate
Open Access
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Fox Chase Cancer Center Researcher Sanjeevani Arora Recognized by JAMA Network Open as a Distinguished Reviewer
07/15/25
1 item of Media coverage
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Fox Chase Cancer Center Researcher Adria Hasan Honored With Scholar-in-Training Award From American Association for Cancer Research
05/2/25
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Fox Chase Cancer Center and the Lewis Katz School of Medicine at Temple University Present Research at the American Association of Cancer Research Annual Meeting 2024
Cai, K. Q., Devarajan, K., Chernoff, J., Flieder, D. B., Nejati, R. M., Einarson, M., Abbosh, P., Edelman, M., Golemis, E. A., Meyer, J. E., Yang, Y., Mitchell, K. A., Campbell, K. S., Chhabra, Y., Galloway, T. J., Zhou, Y., Balachandran, S., Fane, M., Clapper, M., Testa, J. R., Arora, S., Baldwin, D. & Desai, P. A.
04/5/24
1 item of Media coverage
Press/Media