Personal profile
URL
Research interests
Protein structural bioinformatics, protein structure prediction, protein kinase structure, antibody structure
Education/Academic qualification
PhD, Harvard University
Award Date: Jun 10 1993
Bachelor, Harvard
Award Date: Jun 6 1985
External positions
Adjunct Professor, University of Pennsylvania School of Medicine
Adjunct Professor, Drexel University College of Medicine
Keywords
- QD Chemistry
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Collaborations and top research areas from the last five years
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Defining the Active Conformation of Typical Protein Kinase Domains from Substrate-Bound PDB Structures Enables Active-State AlphaFold2 Models for All 437 Human Catalytic Protein Kinases
Gizzio, J., Faezov, B., Xu, Q. & Dunbrack, R. L., Feb 21 2026, In: bioRxiv : the preprint server for biology.Research output: Contribution to journal › Article
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Structural mechanism for noncanonical GPCR signaling in the Hedgehog pathway
Steiner, W. P., Iverson, N., Liu, G., Venkatakrishnan, V., Wu, J., Stepniewski, T. M., Michaelson, Z., Bröckel, J. W., Zhu, J. F., Bruystens, J. G. H., Lee, A., Nelson, I., Bertinetti, D., Arveseth, C. D., Tan, G., Spaltenstein, P., Xu, J., Hüttenhain, R., Kay, M. S. & Herberg, F. W. & 6 others, , Apr 30 2026, (E-pub ahead of print) In: Nature Structural and Molecular Biology.Research output: Contribution to journal › Article › peer-review
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Structure-guided analysis and prediction of human E2-E3 ligase pairing specificity
Jarboe, B. & Dunbrack, R. L., Feb 12 2026, In: bioRxiv : the preprint server for biology.Research output: Contribution to journal › Article
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A Structural Mechanism for Noncanonical GPCR Signal Transduction in the Hedgehog Pathway
Steiner, W. P., Iverson, N., Venkatakrishnan, V., Wu, J., Stepniewski, T. M., Michaelson, Z., Bröckel, J. W., Zhu, J.-F., Bruystens, J., Lee, A., Nelson, I., Bertinetti, D., Arveseth, C. D., Tan, G., Spaltenstein, P., Xu, J., Hüttenhain, R., Kay, M., Herberg, F. W. & Selent, J. & 4 others, , May 27 2025, (bioRxiv : the preprint server for biology).Research output: Working paper › Preprint
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Exploring the potential role of palladin in modulating human CAF/ECM functional units
Dolskii, A., Alcantara dos Santos, S. A., Andrake, M., Franco-Barraza, J., Dunbrack, R. L. & Cukierman, E., Mar 2025, In: Cytoskeleton. 82, 3, p. 175-185 11 p.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations
Prizes
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DeLano Award for Computational Biosciences from the American Society for Biochemistry and Molecular Biology (ASBMB)
Dunbrack, R. (Recipient), Mar 23 2026
Prize: Honorary award
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Press/Media
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University of Utah Health: Hidden Cell 'Message Route' Could Shift Cancer Research
05/11/26
1 item of Media coverage
Press/Media
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