Research output per year
Research output per year
Pofessor, Professor and Director, Lemole Center for Integrated Lymphatic and Vascular Research, Professor, Center for Metabolic Disease Research, Lewis Katz School of Medicine
Research activity per year
The long-term focus of our research program is the identification and characterization of proteins and pathways which play a role in regulation of vascular inflammation, with a current focus on the role of endogenous anti-inflammatory cytokines in this process. We have two distinct, but related areas of investigation: 1- inhibition of vascular occlusive diseases such as atherosclerosis, restenosis, and allograft vasculopathy, and; 2- promotion of angiogenesis to treat peripheral vascular disease. Currently, we are focusing on an endogenous anti-inflammatory cytokine termed IL-19 which: regulates macrophage polarity, macrophage and smooth muscle cell cholesterol homeostasis, smooth muscle and endothelial cell proliferation, and decreases inflammatory mRNA stability, suggesting that this cytokine may represent a therapeutic modality to treat vascular inflammatory diseases.
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Review article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
04/8/24
1 item of Media coverage
Press/Media
05/4/23
1 item of Media coverage
Press/Media
05/2/23 → 05/3/23
16 items of Media coverage
Press/Media