Personal profile
Personal profile
Dr. Daly’s primary areas of research include the epidemiologic and genetic aspects of breast and ovarian cancer, and the translation of this information into effective cancer control approaches.
As Project Co-Leader of the Fox Chase Ovarian SPORE grant, Dr. Daly has initiated studies of ovarian cancer screening modalities, quality of life after prophylactic surgery, serum biomarkers of breast and ovarian cancer risk and developed decision-making tools for women contemplating prophylactic surgery.
As Principal Investigator of the Philadelphia Breast Cancer Family Registry, she is collaborating with institutions worldwide to study the patterns of familial breast and ovarian cancer, gene-environment interactions, and the development of novel, genetic-based therapeutic and preventive strategies.
She chairs the Hereditary Breast and Ovarian Cancer Risk Panel for the National Comprehensive Cancer Network (NCCN) and is a member of its Breast Cancer Screening Guidelines and Breast Cancer Prevention Guidelines Panels.
Dr. Daly is a leader in the design of educational programs in cancer genetics and cancer risk for both high-risk individuals and for their health care providers.
She served as the Principal Investigator of the NSABP breast cancer prevention trials (P1 and STAR).
Dr. Daly is the Editor-in-Chief of the PDQ Cancer Genetics Board. She has co-authored over 225 peer-reviewed publications and has served on a number of editorial boards.
Personal profile
Treatment Philosophy
I consider it an honor and a privilege to have the opportunity to accompany my patients on their cancer journey. I am allowed to witness their strength and courage, to be exposed to the devotion of their families and friends, and to become part of their lives in a very special way.
By extending this care to family members through the risk assessment program, we can work together towards the reduction of risk and prevention of cancer. I like to approach every patient encounter as a mutual learning experience. It is an opportunity for me to share with each patient the latest information about their cancer and treatment or their cancer risk, and give them the tools they need to make informed decisions.
It is also an opportunity for them to teach me something about themselves, about their lives and families, and how they cope with illness and promote their own health. I always feel both drained and enriched after a day in clinic.
Research interests
- Risk Assessment Program Registry
- Philadelphia Breast Cancer Family Registry
- Improving the Estimation and Communication of Ovarian Cancer Risk among BRCA1/2 and Lynch Syndrome Carriers to Optimize Decision Making
- Translation of Genomics into Improvements in Cancer Prevention and Treatment
- COGENT (Communicating Genetic Test Results by Telephone)
- LEGACY (A cohort of youth in families from the Breast Cancer Family Registry)
- Return of Genetic Research: Ethical Issues
URL
External positions
NCCN, Breast Cancer Risk Reduction Panel Member
NCCN, Breast Cancer Screening and Diagnosis Panel Member
NCCN, Genetic/Familial High-Risk Assessment: Breast and Ovarian Panel Member
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Collaborations and top research areas from the last five years
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Efficacy of a sexual quality of life intervention for couples facing metastatic breast cancer: Results of a randomized controlled trial
Reese, J. B., Zimmaro, L. A., Sorice, K. A., Zhang, L., Gorman, J. R., Daly, M. B., Zaleta, A. K. & Porter, L. S., Mar 1 2026, In: Cancer. 132, 5, p. e70334 e70334.Research output: Contribution to journal › Article › peer-review
Open Access -
NCCN Guidelines® Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, Pancreatic, and Prostate, Version 2.2026
Cheng, H. H., Giri, V. N., Goggins, M., Yurgelun, M. B., Karlan, B. Y., Norquist, B. S., Daly, M. B., Pal, T., AlHilli, Z., Arun, B., Churpek, J., Colonna, S., Domchek, S. M., Escobar, M. R., Fejerman, L., Friedman, S., Hagemann, A., Hendrix, A., Huo, D. & Hutton, M. L. & 21 others, , Feb 2026, In: JNCCN Journal of the National Comprehensive Cancer Network. 24, 2, p. 2-10 9 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Personalized Decision-Making in Risk-Reducing Surgery of the Ovaries
Daly, M. B., Egleston, B. L., Lew, K., Bealin, L., Husband, A., Stopfer, J. E., Przybysz, P., Tchuvatkina, O., Wong, Y.-N., Garber, J. E. & Rebbeck, T. R., Mar 2 2026, In: Jama Network Open. 9, 3, p. e263404Research output: Contribution to journal › Article › peer-review
Open Access -
Risks of non-breast, non-ovarian cancers for BRCA1 and BRCA2 pathogenic variant carriers: a prospective cohort study
Kathleen Cuningham Foundation Consortium for Research Into Familial Breast Cancer (kConFab), Mar 4 2026, In: BMC Medicine. 24, 1, 223.Research output: Contribution to journal › Article › peer-review
Open Access -
Steroids, stress, and body mass index interact to accelerate female pubertal development
Houghton, L. C., Siegel, E., Wei, Y., Wudy, S. A., Hartmann, M. F., Stanczyk, F., Knight, J. A., Andrulis, I. L., Bradbury, A. R., Schwartz, L., Buys, S. S., Daly, M. B., John, E. M., Chung, W. K., Santella, R. M., Romeo, R. D. & Terry, M. B., Apr 7 2026, (E-pub ahead of print) In: Journal of Clinical Endocrinology and Metabolism.Research output: Contribution to journal › Article › peer-review
Prizes
Press/Media
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Stress, BMI, and Hormones Linked to Earlier Puberty in Girls
04/13/26 → 04/15/26
3 items of Media coverage
Press/Media
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New Ovarian Cancer Findings from Temple University Health System Described (Personalized Decision-Making in Risk-Reducing Surgery of the Ovaries)
04/9/26
1 item of Media coverage
Press/Media
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Paul Engstrom: Fox Chase Cancer Prevention Pioneer Dies at 89
Clapper, M., Daly, M. & Astsaturov, I.
01/10/26
1 item of Media coverage
Press/Media