Research output per year
Research output per year
Personal profile
Personal profile
Dr. Daly’s primary areas of research include the epidemiologic and genetic aspects of breast and ovarian cancer, and the translation of this information into effective cancer control approaches.
As Project Co-Leader of the Fox Chase Ovarian SPORE grant, Dr. Daly has initiated studies of ovarian cancer screening modalities, quality of life after prophylactic surgery, serum biomarkers of breast and ovarian cancer risk and developed decision-making tools for women contemplating prophylactic surgery.
As Principal Investigator of the Philadelphia Breast Cancer Family Registry, she is collaborating with institutions worldwide to study the patterns of familial breast and ovarian cancer, gene-environment interactions, and the development of novel, genetic-based therapeutic and preventive strategies.
She chairs the Hereditary Breast and Ovarian Cancer Risk Panel for the National Comprehensive Cancer Network (NCCN) and is a member of its Breast Cancer Screening Guidelines and Breast Cancer Prevention Guidelines Panels.
Dr. Daly is a leader in the design of educational programs in cancer genetics and cancer risk for both high-risk individuals and for their health care providers.
She served as the Principal Investigator of the NSABP breast cancer prevention trials (P1 and STAR).
Dr. Daly is the Editor-in-Chief of the PDQ Cancer Genetics Board. She has co-authored over 225 peer-reviewed publications and has served on a number of editorial boards.
Personal profile
Treatment Philosophy
I consider it an honor and a privilege to have the opportunity to accompany my patients on their cancer journey. I am allowed to witness their strength and courage, to be exposed to the devotion of their families and friends, and to become part of their lives in a very special way.
By extending this care to family members through the risk assessment program, we can work together towards the reduction of risk and prevention of cancer. I like to approach every patient encounter as a mutual learning experience. It is an opportunity for me to share with each patient the latest information about their cancer and treatment or their cancer risk, and give them the tools they need to make informed decisions.
It is also an opportunity for them to teach me something about themselves, about their lives and families, and how they cope with illness and promote their own health. I always feel both drained and enriched after a day in clinic.
Research interests
- Risk Assessment Program Registry
- Philadelphia Breast Cancer Family Registry
- Improving the Estimation and Communication of Ovarian Cancer Risk among BRCA1/2 and Lynch Syndrome Carriers to Optimize Decision Making
- Translation of Genomics into Improvements in Cancer Prevention and Treatment
- COGENT (Communicating Genetic Test Results by Telephone)
- LEGACY (A cohort of youth in families from the Breast Cancer Family Registry)
- Return of Genetic Research: Ethical Issues
URL
External positions
NCCN, Breast Cancer Risk Reduction Panel Member
NCCN, Breast Cancer Screening and Diagnosis Panel Member
NCCN, Genetic/Familial High-Risk Assessment: Breast and Ovarian Panel Member
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Collaborations and top research areas from the last five years
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Changes in Risk Tolerance for Ovarian Cancer Prevention Strategies during the COVID-19 Pandemic: Results of a Discrete Choice Experiment
Egleston, B. L., Daly, M. B., Lew, K., Bealin, L., Husband, A. D., Stopfer, J. E., Przybysz, P., Tchuvatkina, O., Wong, Y. N., Garber, J. E. & Rebbeck, T. R., Feb 2025, In: Medical Decision Making. 45, 2, p. 168-176 9 p.Research output: Contribution to journal › Article › peer-review
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Efficacy of a couple-based intervention addressing sexual concerns for breast cancer survivors: Results of a randomized controlled trial
Reese, J. B., Lepore, S. J., Sorice, K. A., Zimmaro, L. A., Hasler, J., Handorf, E., Daly, M. B., Zaleta, A. K., Westbrook, K. & Porter, L. S., Jan 1 2025, In: Cancer. 131, 1, p. e35685 e35685.Research output: Contribution to journal › Article › peer-review
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Hormonal Contraception and Breast Cancer Risk for Carriers of Germline Mutations in BRCA1 and BRCA2
Phillips, K. A., Kotsopoulos, J., Domchek, S. M., Terry, M. B., Chamberlain, J. A., Bassett, J. K., Aeilts, A. M., Andrulis, I. L., Buys, S. S., Cui, W., Daly, M. B., Eisen, A. F., Foulkes, W. D., Friedlander, M. L., Gronwald, J., Hopper, J. L., John, E. M., Karlan, B. Y., Kim, R. H. & Kurian, A. W. & 9 others, , Feb 1 2025, In: Journal of Clinical Oncology. 43, 4, p. 422-431 10 p.Research output: Contribution to journal › Article › peer-review
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Menopausal hormone therapy: assessing associations with breast and colorectal cancers by familial risk
KConFab Investigators, Feb 1 2025, In: JNCI Cancer Spectrum. 9, 1, pkae121.Research output: Contribution to journal › Article › peer-review
Open Access -
Physical Activity during Adolescence and Early Adulthood and Breast Cancer Risk before Age 40 Years
Kehm, R. D., Genkinger, J. M., Knight, J. A., MacInnis, R. J., Liao, Y., Li, S., Weideman, P. C., Chung, W. K., Kurian, A. W., Colonna, S. V., Andrulis, I. L., Buys, S. S., Daly, M. B., John, E. M., Hopper, J. L. & Terry, M. B., Jan 1 2025, In: Cancer Epidemiology Biomarkers and Prevention. 34, 1, p. 108-116 9 p.Research output: Contribution to journal › Article › peer-review
Open Access
Prizes
Press/Media
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New NCCN Patient Resource Shares Latest Understanding Of Genetic Testing To Guide Patient Decision Making
01/16/25
92 items of Media coverage
Press/Media
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Cancer Genetic Risk Assessment Guidelines Expand to Meet Growing Understanding of Hereditary Risk
11/19/24
1 item of Media coverage
Press/Media
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NCCN Guidelines Have Expanded to Meet Growing Understanding of Hereditary Risk
11/8/24
1 item of Media coverage
Press/Media