Personal profile
Research interests
My research focuses on key factors influencing cardiometabolic health and cancer treatment, including disease staging, social determinants of health, and microbiome characteristics. I am particularly interested in understanding how patients with specific diseases or cancers differ in social variables and microbiome composition compared to healthy populations. My interests span the following areas:
- Microbiome and Disease: Exploring microbiome differences across various health states to develop novel methodologies for utilizing microbiome data in clinical outcome predictions, paving the way for microbiome-informed precision medicine.
- Bayesian Data Analysis: Employing Bayesian methods for analyzing high-dimensional health data or electronic medical record (EMR) to improve the precision and reliability of health predictions and insights.
- Cardiometabolic Health and Cancer Treatment: Investigating the progression and staging of cardiometabolic diseases to better understand how different stages impact overall health outcomes and disease trajectories.
- Health Disparities and Social Determinants: Examining how social and neighborhood factors—including socioeconomic status, resource access, and lifestyle choices—affect cardiometabolic outcomes, illuminating the interplay between environment, behavior, and health
Education/Academic qualification
PhD, PhD, Biostatistics
Aug 2019 → Apr 2024
Award Date: Apr 30 2024
Master, MS, Statistics, Georgia State University
Jun 2016 → May 2018
Award Date: May 31 2018
Master, MS, Medicinal Chemistry, Nankai University
Sep 2011 → Jun 2014
Award Date: Jun 30 2014
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Collaborations and top research areas from the last five years
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BCGLMs: Bayesian modeling for disease prediction using compositional microbiome features
Zhang, L., Ding, Z. & Yi, N., 2026, In: Bioinformatics Advances. 6, 1, p. vbag041 vbag041.Research output: Contribution to journal › Article › peer-review
Open Access -
Persistent poverty, glycemic control and adverse COVID-19 outcomes: a retrospective study using real-world data
Tanaka, S., Williams, S., Zhang, L., Yi, N., Garvey, W. T., Cherrington, A. L. & Howell, C. R., Dec 2026, In: BMC International Health and Human Rights. 26, 1, p. 159 159.Research output: Contribution to journal › Article › peer-review
Open Access -
Adding social determinants of health to the equation: Development of a cardiometabolic disease staging model using clinical and social determinants of health to predict type 2 diabetes
Howell, C. R., Tanaka, S., Zhang, L., Carson, A. P., Yi, N., Shikany, J. M., Garvey, W. T. & Cherrington, A. L., May 2025, In: Diabetes, Obesity and Metabolism. 27, 5, p. 2454-2462 9 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
ASO Visual Abstract: The Utility of Preoperative PET/CT in Patients with Clinically High-Risk Melanoma
Papai, E., Ntoh, K., Zhang, L., Yu, J. Q., Olszanski, A. J., Villano, A. M., Porpiglia, A. S., Reddy, S. S., Farma, J. M. & Greco, S. H., Sep 3 2025, In: Annals of Surgical Oncology. 1 p.Research output: Contribution to journal › Editorial
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Bayesian compositional generalized linear mixed models for disease prediction using microbiome data
Zhang, L., Zhang, X., Leach, J. M., Rahman, A. K. M. F., Howell, C. R. & Yi, N., Apr 5 2025, In: BMC Bioinformatics. 26, 1, p. 98 98.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations