Personal profile
Research interests
Our lab conducts epigenome-wide studies in colorectal cancer (CRC) and assisted reproductive technology (ART). We are interested in studying disparities (racial and age of onset) in the incidence and outcome of CRC. In the ART project, we are looking into various clinically modifiable factors that affects DNA methylation in children conceived through ART. We are also conducting longitudinal studies in the ART population.
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Collaborations and top research areas from the last five years
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Abnormal epigenetic aging of epigenetic outliers in normal colon mucosa from colorectal cancer patients
Schultz, B. M., Ayeotan, O., Rana, J. N., Litwin, S., Basickes, S., Sapienza, C. & Ghosh, J., Jan 7 2026, In: Scientific Reports. 16, 1, p. 4022 1 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Polθ activity modulates sensitivity to standard therapies in DNMT3A-deficient leukemia
Le, B. V., Vekariya, U., Toma, M. M., Nieborowska-Skorska, M., Caron, M.-C., Gozdecka, M., Haydar, Z., Walsh, M., Ghosh, J., Vaughan-Williams, E., Podszywalow-Bartnicka, P., Kukuyan, A.-M., Ziolkowska, S., Atkins, J., Hadzijusufovic, E., Chandramouly, G., Nejati, R., Piwocka, K., Pomerantz, R. & Vassiliou, G. S. & 8 others, , Mar 17 2026, In: Cell Reports Medicine. 7, 3, p. 102687 29 p., 102687.Research output: Contribution to journal › Article › peer-review
Open Access -
Association between gut microbiota and CpG island methylator phenotype in colorectal cancer
Park, P. H., Keith, K., Calendo, G., Jelinek, J., Madzo, J., Gharaibeh, R. Z., Ghosh, J., Sapienza, C., Jobin, C. & Issa, J.-P. J., Dec 31 2024, In: Gut Microbes. 16, 1, p. 2363012 18 p., 2363012.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Epigenetic mechanisms regulate sex differences in cardiac reparative functions of bone marrow progenitor cells
Thej, C., Roy, R., Cheng, Z., Garikipati, V. N. S., Truongcao, M. M., Joladarashi, D., Mallaredy, V., Cimini, M., Gonzalez, C., Magadum, A., Ghosh, J., Benedict, C., Koch, W. J. & Kishore, R., Apr 29 2024, In: npj Regenerative Medicine. 9, 1, p. 17 16 p., 17.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
DNA polymerase θ protects leukemia cells from metabolically induced DNA damage
Vekariya, U., Toma, M., Nieborowska-Skorska, M., Le, B. V., Caron, M. C., Kukuyan, A. M., Sullivan-Reed, K., Podszywalow-Bartnicka, P., Chitrala, K. N., Atkins, J., Drzewiecka, M., Feng, W., Chan, J., Chatla, S., Golovine, K., Jelinek, J., Sliwinski, T., Ghosh, J., Matlawska-Wasowska, K. & Chandramouly, G. & 18 others, , May 11 2023, In: Blood. 141, 19, p. 2372-2389 18 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations
Press/Media
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Data on Leukemia Detailed by Researchers at Temple University (Pol9 Activity Modulates Sensitivity To Standard Therapies In Dnmt3a-deficient Leukemia)
Wasik, M. A., Skorski, T. & Ghosh, J.
04/17/26
1 item of Media coverage
Press/Media
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Temple University Details Findings in Leukemia (Polth activity modulates sensitivity to standard therapies in DNMT3A-deficient leukemia)
03/31/26
1 item of Media coverage
Press/Media