Personal profile
Personal profile
Specialties
- Surgical Oncology ;
- Hepatobiliary and Pancreatic Surgery
Areas of Expertise
Neuroendocrine Tumors, Sarcoma, Colorectal Cancer, Melanoma, Pancreatic Cyst, Liver, Gall Bladder & Bile Duct Cancer, Pancreatic Cancer, Stomach (Gastric) Cancer, GIST (Gastrointestinal Stromal Tumor)
Treatment Focus
Cancers of the liver, gall bladder, bile ducts, and pancreas; Colorectal liver metastases; Hepatic atery infusion pump chemotherapy; Robotic surgery; Minimally invasive surgery
Treatment Philosophy
I’m honored to be part of the talented team at Fox Chase Cancer Center. As a surgeon with specialty training in both Surgical Oncology and Hepato-Pancreato-Biliary surgery, I am focused on caring for people with benign, pre-cancerous, and malignant (cancerous) diseases of the liver, gallbladder, bile ducts, and pancreas, as well as cancers that have spread to the liver from the colon.
I completed medical school and general surgery residency at Vanderbilt University Medical Center in Nashville, Tennessee. During residency I completed a two-year research fellowship studying therapeutic resistance in pancreatic cancer, and I spent an additional two years completing a MS in Biomedical Informatics. The skills I gained during these research fellowships have been useful in almost every task I encounter, whether they are administrative, clinical, or research oriented.
My clinical training in Surgical Oncology was completed at Memorial Sloan Kettering Cancer Center. In addition to training in the full breadth of surgical oncology, I spent my final year of training specifically focused on diseases of the liver, gallbladder, bile ducts, and pancreas. This involved extensive training in robotic and laparoscopic approaches to remove tumors of the liver and pancreas, placement of hepatic artery infusion chemotherapy pumps for the treatment of colorectal liver metastases and intrahepatic cholangiocarcinoma, and the use of heat (ablation) and electricity (irreversible electroporation) to treat colorectal liver metastases.
The most formative training I received, however, has been helping family members through cancer treatment. My priority is to help you and your family members through each stage of treatment with the same level of diligence, compassion and honesty that I would give to my own family. I chose to practice at Fox Chase not only because it is a storied institution with dedicated specialists providing the highest quality of care, but also because of the profound sense of camaraderie, team work, and institutional pride evident in every interaction here.
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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A Randomized, Controlled Trial Evaluating Perioperative Risk-stratification and Risk-based, Protocol-driven Management After Elective Major Cancer Surgery
Esnaola, N. F., Chelluri, R., Castellanos, J., Altman, A., Chen, D. Y. T., Chu, C., Farma, J. M., Haber, A., Sheriff, F., Huang, C., Kutikov, A., Patel, S., Patrick, K., Reddy, S., Rubin, S., Viterbo, R., Ridge, J. A., Edelman, M., Ross, E. & Smaldone, M. & 1 others, , Mar 2025, In: Annals of Surgery. 281, 3, p. 395-403 9 p.Research output: Contribution to journal › Article › peer-review
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Biliary Tract Cancers, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology
Benson, A. B., D'Angelica, M. I., Abrams, T., Ahmed, A., Akce, M., Anaya, D. A., Anders, R., Are, C., Aye, L., Bachini, M., Baker, M., Binder, D., Brown, D. B., Burgoyne, A., Castellanos, J., Cloyd, J., Cullinan, D., Franses, J., Glazer, E. S. & Harris, W. & 21 others, , Sep 1 2025, In: JNCCN Journal of the National Comprehensive Cancer Network. 23, 9, p. 403-418 16 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Editor's Note: Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer
Nagathihalli, N. S., Castellanos, J. A., Lamichhane, P., Messaggio, F., Shi, C., Dai, X., Rai, P., Chen, X., VanSaun, M. N. & Merchant, N. B., Jun 16 2025, In: Cancer Research. 85, 12, p. 2338 1 p.Research output: Contribution to journal › Comment/debate
Open Access -
Starting a New HAI Program: Building a Team
Crocker, A., Castellanos, J. & Ocuin, L., Jan 1 2025, Hepatic Arterial Infusion for Malignancy. Springer Science+Business Media, p. 243-245 3 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Biliary Tract Cancers, Version 2.2023 Featured Updates to the NCCN Guidelines
Benson, A. B., D’Angelica, M. I., Abrams, T., Abbott, D. E., Ahmed, A., Anaya, D. A., Anders, R., Are, C., Bachini, M., Binder, D., Borad, M., Bowlus, C., Brown, D., Burgoyne, A., Castellanos, J., Chahal, P., Cloyd, J., Covey, A. M., Glazer, E. S. & Hawkins, W. G. & 21 others, , Jul 2023, In: Journal of the National Comprehensive Cancer Network : JNCCN. 21, 7, p. 694-704 11 p.Research output: Contribution to journal › Article › peer-review
Open Access161 Scopus citations
Press/Media
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SPONSORED: Understanding the rise in colorectal cancer in under-50s
Castellanos, J. A. & Cann, C. G.
03/30/26
1 item of Media coverage
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Philadelphia Magazine Names 142 Fox Chase Cancer Center Physicians 'Top Doctors'
Mantia-Smaldone, G. M., Vijayvergia, N., Borghaei, H., Weiss, S. E., Kumar, R., Khanal, R., Frosch, Z. A., Flieder, D. B., Chen, D. Y., Plimack, E. R., Manley, C. J., Nejati, R. M., Ehya, H., Kutikov, A., Sherry, D. R., Hallman, M. A., Uzzo, R. G., Patel, S. A., Daly, M., Viterbo, R., Curcillo, P. G., Bleicher, R., Edelman, M., Greco, S. H., Miyamoto, C. T., von Mehren, M., Chwistek, M., Galloway, T. J., Jain, A., Meyer, J. E., Castellanos, J. A., Farma, J. M., Weinberg, D. S., Friedberg, J., Wasik, M. A., Zibelman, M. R., Wang, Y. L., Astsaturov, I., Olszanski, A. J., Simhan, J., Friedlander, J. I., Cohn, J., Sterious, S., Wei, S., Giri, A. P., Berman, A. T., Loren, D. E., McCue, P. A., Abdelmessieh, P., Ahmad, D., Messmer, M., Ghiraldi, E. M., Horwitz, E. M., Correa, A. F., Yu, J. Q., Smaldone, M. C., Villano, A. M., Aphale, A., McShane, M. M., Kumar, S. S., Walchak, A., Wookey, V. B., Wong, J. K., Nakhoda, S. K., Bauman, J., Williams, A. D., Hall, M. J., Fung, H. C., Reddy, S. S. & Geynisman, D.
04/22/25
1 item of Media coverage
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310 Temple Health Physicians Named 'Top Doctors' by Philadelphia Magazine
Mantia-Smaldone, G. M., Vijayvergia, N., Borghaei, H., Weiss, S. E., Kumar, R., Khanal, R., Flieder, D. B., Chen, D. Y., Plimack, E. R., Dotan, E., Manley, C. J., Hernandez, E., Nejati, R. M., Ehya, H., Kutikov, A., Hallman, M. A., Uzzo, R. G., Patel, S. A., Viterbo, R., Curcillo, P. G., Bleicher, R., Edelman, M., Greco, S. H., Miyamoto, C. T., von Mehren, M., Chwistek, M., Jain, A., Meyer, J. E., Castellanos, J. A., Farma, J. M., Weinberg, D. S., Friedberg, J., Wasik, M. A., Zibelman, M. R., Wang, Y. L., Astsaturov, I., Olszanski, A. J., Simhan, J., Friedlander, J. I., Cohn, J., Sterious, S., Galloway, T. J., Wei, S., Giri, A. P., Berman, A. T., Loren, D. E., McCue, P. A., Abdelmessieh, P., Ahmad, D., Messmer, M., Horwitz, E. M., Correa, A. F., Yu, J. Q., Smaldone, M. C., Villano, A. M., Aphale, A., McShane, M. M., Kumar, S. S., Walchak, A., Nakhoda, S. K., Erkmen, C., Bauman, J., Williams, A. D., Hall, M. J., Fung, H. C., Reddy, S. S. & Geynisman, D.
05/22/24
1 item of Media coverage
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Philadelphia Magazine Names 133 Fox Chase Cancer Center Physicians 'Top Doctors'
Mantia-Smaldone, G. M., Vijayvergia, N., Borghaei, H., Weiss, S. E., Kumar, R., Khanal, R., Flieder, D. B., Chen, D. Y., Plimack, E. R., Dotan, E., Manley, C. J., Nejati, R. M., Ehya, H., Kutikov, A., Hallman, M. A., Uzzo, R. G., Wei, S., Patel, S. A., Viterbo, R., Curcillo, P. G., Bleicher, R., Edelman, M., Giri, A. P., Miyamoto, C. T., von Mehren, M., Chwistek, M., Galloway, T. J., Jain, A., Meyer, J. E., Castellanos, J. A., Farma, J. M., Weinberg, D. S., Friedberg, J., Wasik, M. A., Zibelman, M. R., Wang, Y. L., Astsaturov, I., Olszanski, A. J., Simhan, J., Friedlander, J. I., Cohn, J., Sterious, S., Berman, A. T., Loren, D. E., Greco, S. H., McCue, P. A., Abdelmessieh, P., Ahmad, D., Messmer, M., Horwitz, E. M., Correa, A. F., Yu, J. Q., Smaldone, M. C., Villano, A. M., Aphale, A., McShane, M. M., Kumar, S. S., Walchak, A., Nakhoda, S. K., Bauman, J., Williams, A. D., Hall, M. J., Fung, H. C., Reddy, S. S. & Geynisman, D.
04/22/24 → 04/23/24
2 items of Media coverage
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Special Tea Held at Fox Chase Kicks Off Fundraising for 2024 Paws for the Cause Dog Walk
04/3/24
1 item of Media coverage
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