Research output per year
Research output per year
Personal profile
Personal profile
Treatment Philosophy
I chose to stay at Fox Chase as an attending physician for the love of the institutional environment and the great patients I am so privileged to treat. I love my work for the great team spirit cultivated among my colleagues, physicians and nurses. I am extremely grateful to the fact that patients are at the center of everybody’s attention. It is easy for me to do my job in such an atmosphere of concern and indefatigable compassion.
Fox Chase also offers me an opportunity to work both in the clinic and in the lab, where I am studying cancer biology with the goal to design better treatment options for the patients. In my field of gastrointestinal malignancies, I am convinced that the treatment choices for each individual cancer patient will soon be defined by the molecular makeup of their cancer cells. This knowledge can help us match the treatment strategies with the biology of individual patient’s tumors. I am interested to translate the knowledge about cancer available in the lab to the clinic by conducting hypothesis-driven clinical trials.
I am deeply convinced that the best way to help our patients is to push the boundaries by doing clinical and basic research.
Research interests
Cancer Metabolism and signaling
- The central role for sterol metabolism in regulation of cell growth and signaling
- Pancreatic cancer biology and "smart drugs" for treatment of pancreatic cancer
- Translating therapeutic concepts to the clinic using the platform of patient-derived avatar models and genetically engineered pancreatic cancer models
URL
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Breaking barriers: Smart vaccine platforms for cancer immunomodulation
Gomari, M. M., Ghantabpour, T., Pourgholam, N., Rostami, N., Hatfield, S. M., Namazifar, F., Abkhiz, S., Eslami, S. S., Ramezanpour, M., Darestanifarahani, M., Astsaturov, I. & Bencherif, S. A., May 2025, In: Cancer Communications. 45, 5, p. 529-571 43 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Racial/Ethnic Differences and Effects of Clinical/Socioeconomic Factors on Time from Diagnosis to Treatment in Pancreatic Cancer
Sridharan, A., Dotan, E., Dorta, M., Vemula, N., Handorf, E., Deng, M., Renning, A., Sorice, K., Laderman, L., Whittington, K., Cukierman, E., Astsaturov, I., Vijayvergia, N., Meyer, J. E., Reddy, S. S. & Lynch, S. M., Feb 15 2025, In: Journal of Gastrointestinal Cancer. 56, 1, p. 67 67.Research output: Contribution to journal › Article › peer-review
Open Access -
Food Insecurity and Dietary Quality in African American Patients with Gastrointestinal Cancers: An Exploratory Study
Dratsky, D., McGillivray, E., Mittal, J., Handorf, E. A., Berardi, G., Astsaturov, I., Hall, M. J., Yeh, M. C., Jain, R. & Fang, C. Y., Sep 2024, In: Nutrients. 16, 18, 3057.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Large-scale analysis of CDH1 mutations defines a distinctive molecular subset with treatment implications in gastric cancer
Wang, J., Xiu, J., Battaglin, F., Arai, H., Soni, S., Zhang, W., Goldberg, R. M., Philip, P. A., Seeber, A., Hwang, J. J., Shields, A. F., Marshall, J. L., Astaturov, I., Liu, T., Lockhart, A. C., Korn, W. M., Shen, L. & Lenz, H. J., Aug 30 2024, In: npj Precision Oncology. 8, 1, p. 214 214.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Protocol for isolating extracellular vesicles from pancreatic cancer cells for liver metastatic niche research
Casabianca, A., Bellina, M., Dudgeon, C., Nezhad, M. S., Harris, C., Fiore, S., Bernet, A., Narrow, W., Prela, O., Wang, L., Astsaturov, I., Mehlen, P. & Carpizo, D. R., Sep 20 2024, In: Star Protocols. 5, 3, p. 103256 103256.Research output: Contribution to journal › Article › peer-review
Open Access
Prizes
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The Paul F. Engstrom Professorship in Oncology
Astsaturov, I. (Recipient), 2023
Prize: Other distinction
Press/Media
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Philadelphia Magazine Names 142 Fox Chase Cancer Center Physicians 'Top Doctors'
Mantia-Smaldone, G. M., Vijayvergia, N., Borghaei, H., Weiss, S. E., Bodor, J. N., Kumar, R., Khanal, R., Frosch, Z. A., Flieder, D. B., Chen, D. Y., Plimack, E. R., Manley, C. J., Nejati, R. M., Ehya, H., Kutikov, A., Rubin, S. C., Sherry, D. R., Hallman, M. A., Uzzo, R. G., Patel, S. A., Daly, M., Viterbo, R., Curcillo, P. G., Bleicher, R., Wong, J. K., Reddy, S. S., Edelman, M., Nakhoda, S. K., Greco, S. H., Miyamoto, C. T., Bauman, J., von Mehren, M., Yu, J. Q., Chwistek, M., Galloway, T. J., Williams, A. D., Jain, A., Meyer, J. E., Castellanos, J. A., Hall, M. J., Ahmad, D., Farma, J. M., Weinberg, D. S., Friedberg, J., Wasik, M. A., Zibelman, M. R., Wang, Y. L., Geynisman, D., Astsaturov, I., Olszanski, A. J., Simhan, J., Friedlander, J. I., Cohn, J., Sterious, S., Ghiraldi, E. M., Wei, S., Aphale, A., McShane, M. M., Kumar, S. S., Walchak, A., Giri, A. P., Sharda, P. & Messmer, M.
04/22/25
1 item of Media coverage
Press/Media
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310 Temple Health Physicians Named 'Top Doctors' by Philadelphia Magazine
Mantia-Smaldone, G. M., Vijayvergia, N., Borghaei, H., Weiss, S. E., Bodor, J. N., Kumar, R., Berman, A. T., Khanal, R., Flieder, D. B., Chen, D. Y., Plimack, E. R., Dotan, E., Manley, C. J., Hernandez, E., Nejati, R. M., Ehya, H., Kutikov, A., Rubin, S. C., Hallman, M. A., Uzzo, R. G., Patel, S. A., Viterbo, R., Curcillo, P. G., Bleicher, R., Reddy, S. S., Edelman, M., Nakhoda, S. K., Greco, S. H., Miyamoto, C. T., Bauman, J., von Mehren, M., Yu, J. Q., Chwistek, M., Williams, A. D., Jain, A., Meyer, J. E., Castellanos, J. A., Hall, M. J., Ahmad, D., Farma, J. M., Weinberg, D. S., Friedberg, J., Wasik, M. A., Zibelman, M. R., Messmer, M., Wang, Y. L., Geynisman, D., Astsaturov, I., Olszanski, A. J., Simhan, J., Friedlander, J. I., Cohn, J., Sterious, S., Galloway, T. J., Wei, S., Aphale, A., McShane, M. M., Kumar, S. S., Walchak, A., Giri, A. P. & Sharda, P.
05/22/24
1 item of Media coverage
Press/Media